肺转移性脂肪肉瘤1例及文献复习  

Analysis of one patient with metastatic liposarcoma of lung and literature review

作　　者：王妍敏[1] 韩锋锋[1] 管雯斌[2] 彭娟[1] 孙晋渊[1] 郭雪君[1] 

机构地区：[1]上海交通大学医学院附属新华医院呼吸内科,200092 [2]上海交通大学医学院附属新华医院病理科,200092

出　　处：《国际呼吸杂志》2017年第15期1144-1149,共6页International Journal of Respiration

摘　　要：目的探讨肺转移性脂肪肉瘤的临床和病理特点，减少误诊、漏诊。方法对收治的1例肺转移性脂肪肉瘤患者的临床资料进行回顾性分析。结果本例为55岁男性，因“咳嗽伴气促1个月，加重1d”入院。CT和胸水B超示右侧包裹性胸腔积液，肿瘤声学造影示右肺占位。胸外科手术切除右肺肿块，术后病理提示圆细胞型脂肪肉瘤。术后患者出现四肢、臀部、腹部巨大肿块，且生长迅速，术后给予放化疗及对症支持治疗。结论肺原发性和转移性脂肪肉瘤临床均少见，症状隐匿、缺乏特异性，易误诊，B超肿瘤声学造影有助于早期鉴别。除手术切除外，生长迅速、多发转移者可考虑术前、术后联合放化疗。Objective To investigate the pathological and clinical features of metastatic liposarcoma of lung in order to reduce the misdiagnosis and missed diagnosis rates. Methods The clinical data of one patient with metastatic liposarcoma of lung in our hospital was retrospectively analyzed. Results A 55 yearold male complained of having cough and chest distress for one month. Chest CT and ultrasonography showed encapsulated effusion. The pathological report of surgery was liposarcoma. After that, large masses were found in limbs, butlocks and abdomen, progressing quickly. Postoperative radiotherapy ,and chemotherapy were performed. Conclusions IAposarcoma of lung is rare and uncharacteristic. It tends to be easily misdiagnosed and missed diagnosed. Clinicians should enhance awareness of this disease. Ultrasonic contrast is helpful for the diagnosis. If the tumor grows fast, we suggest combined therapy of surgery, radiotherapy and chemotherapy.

关 键 词：肺转移性脂肪肉瘤 临床病理特点 

分 类 号：R734.2[医药卫生—肿瘤]