巩膜瓣下双池效应式小梁切除术联合可调整缝线治疗原发性闭角型青光眼的临床疗效和安全性  

Study on the efffcacy and safety of double pool type trabeculectomy under sclera flap joint adjustable suture in treatment of glaucoma

作　　者：李依焕 杨阳 薛国民[1] 

机构地区：[1]陕西省榆林市第一医院眼科,陕西榆林719000 [2]陕西省榆林市星元医院眼科,陕西榆林719000

出　　处：《临床和实验医学杂志》2017年第18期1860-1863,共4页Journal of Clinical and Experimental Medicine

摘　　要：目的评价巩膜瓣下双池效应式小梁切除术联合可调整缝线治疗原发性闭角型青光眼的临床疗效及安全性。方法选取120例原发性闭角型青光眼患者作为研究对象,按照随机分层分组法分为治疗组与对照组,各60例,对照组患者给予传统小梁切除术治疗,治疗组患者给予巩膜瓣下双池效应式小梁切除术联合可调整缝线治疗,均随访12个月,比较两组患者术后1周、术后1月时眼压平均值,术后1年患眼功能性滤泡和非功能性滤泡比率,以及术后早期前房深度情况。结果两组患者术后1周、术后1个月时眼压平均值比较,无显著差异(P>0.05),术后1年时两组患者眼压均较术后1周时明显增高(P<0.05),但治疗组眼压增高幅度明显少于对照组(P<0.05);治疗组患者术后1年患眼功能性滤泡比率明显高于对照组(P<0.05),非功能性滤泡比率明显低于对照组(P<0.05);治疗组患者术后早期出现Ⅰ度浅前房3例,浅前房发生率为4.2%;对照组患者术后早期出现Ⅰ度浅前房11例、Ⅱ度浅前房2例、Ⅲ度浅前房1例,浅前房发生率为20.0%,治疗组早期浅前房发生率明显低于对照组,差异有统计学意义(P<0.05)。结论巩膜瓣下双池效应式小梁切除术联合可调整缝线治疗原发性闭角型青光眼具有稳定眼压效果好、近期安全性高等优点,值得推广应用。Objective To evaluate the eficacy and safety of double pool type trabeculectomy under sclera flap joint adjustable suture in treatment of glaucoma. Methods A total of 120 patients with glaucoma in this hospital were allocated as research objects,they were divided into treatment group and control group（ n = 60） according to randomized stratified grouping method,and patients in control group were treated with traditional trabeculectomy,and patients in treatment group were given with double pool type trabeculectomy under sclera flap joint adjustable suture therapy,and they were followed up for 12 months. The average value of intraoccular pressure had been compared between patients of these two groups in 1 week and 1 month after operation,the functional and non-functional follicular ratio after 1 year and early postoperative anterior chamber depth were compared between these 2 groups. Results The difference in intraoccular pressure in patients at postoperative 1 week and 1 month between these 2 groups was not significant（ P〉0. 05）,but it in postoperative 1 year was significantly higher than that of postoperative 1 week（ P〈0. 05）,but the amplititude of increased intraocular pressure was obviously lower in treatment group than that of control group（ P〈0. 05）.The functional follicular ratio of eyes in patients of treatment group after 1 year was significantly higher than that of patients in control group（ P〈0. 05）,and the non-functional follicular proportion was significantly lower than that of control group（ P〈0. 05）. 3 patients in early postoperative treatment group showed I degree shallow anterior chanmber,the incidence of shallow anterior chamber was 4. 2%. Patients in control group with early postoperativeⅠdegree shallow anterior chamber were 11 cases,Ⅱ degrees of shallow anterior chamber in 2 cases,Ⅲ degrees of shallow anterior chamber in 1 case,the incidence of shallow anterior chamber was 20%,and the incidence of shallow anterior chamber in early treatment group was obviou

关 键 词：原发性闭角型青光眼 双池效应式小梁切除术 可调整缝线 

分 类 号：R779.6[医药卫生—眼科]