两种光学生物测量仪在中国青少年人群中应用的比较  

Comparison of ocular biometry by two kinds of optical biometers in Chinese adolescents

作　　者：韦燕凯 粘红[1] 谷天瀑 魏瑞华[1] 

机构地区：[1]天津医科大学眼科医院,天津医科大学眼科研究所,天津市300384

出　　处：《眼科新进展》2017年第9期835-838,共4页Recent Advances in Ophthalmology

基　　金：国家自然科学基金面上项目资助(编号:81570834)~~

摘　　要：目的评估两种光学生物测量仪(Lenstar LS900~与SW-9000)对青少年眼球生物测量结果的重复性,并比较两种仪器测量值的一致性。方法采用前瞻性研究,纳入65例屈光不正患者,分别用SW-9000与Lenstar LS900~进行右眼眼球生物测量,应用单因素方差分析评估仪器的可重复性,应用Bland-Altman散点图对两种仪器测量值进行一致性评价。结果 Lenstar LS900~测量指标AL、K1、K2、CCT、AD、LT、PD的重复性良好,ICC均大于0.90;WTW略差,但仍大于0.88。SW-9000测量指标AL、K1、K2、CCT的重复性良好,ICC均大于0.9,其余参数重复性较差。将两种仪器重复性均良好的AL、K1、K2、CCT分别进行比较,发现SW-9000所测AL、CCT比Lenstar LS900~略长,且差异均有统计学意义(均为P<0.05);而K1、K2均无明显差异(均为P>0.05)。此外两种仪器间AL、K1、K2、CCT均存在密切的线性相关(均为r>0.97,均为P<0.01)。Bland-Altman散点图显示,两种仪器测量指标的95%Lo A分别为AL:-0.057~0.133 mm;K1:-0.456~0.369 D;K2:-0.388~0.549 D;CCT:-3.483~8.016μm。结论对于8~18岁青少年人群,Lenstar LS900~与SW-9000眼球生物测量指标(包括AL、K1、K2、CCT)均具有良好的重复性,SW-9000与Lenstar LS900~测量参数AL、K1、K2、CCT相关性高,且4个参数95%Lo A在临床上可接受,一致性良好。Objeetive To evaluate the repeatability and agreement of two optical biometers （ Lenstar LS900 and SW-9000） for ocular biometry in Chinese adolescents. Methods A prospective study was conducted which included 65 ametropic patients, with an average age of （ 11.45 ±2.67） years （ age ranging from 8 to 18 years）. The ocu- lar biometry for right eyeball was performed with Lenstar LS900 and SW-9000 respec- tively,followed by evaluation of the repeatability of the two biometers using one-way a- nalysis of variance, and the agreement of the two instruments using the Bland-Altman plot. Results The repeatability of parameters measured by Lenstar LS900 , inclu- ding axial length （AL） ,K value in the flattest meridian （ K1 ） ,K value in the steepest meridian （K2）, central corneal thickness （ CCT）, anterior depth （ AD）, lens thickness （LT） ,pupil diameter （ PD）, was well,and all intraclass correlation coefficient （ ICC ） 〉 0.9;the repeatability of white to white （WTW） was inferior to other parameters,but it was still 〉0. 88. The repeatability of AL,K1 ,K2, CCT measured by SW-9000 was good, with their ICC 〉 0.9, but the repeatability of other parameters was poor. The parameters with good repeatability including AL,K1,K2, CCT measured by SW-9000 and Lenstar Ls900 were compared respectively, and the results showed that AL and CCT exam- ined by SW-9000 were slightly longer than those measured by Lenstar LS900 , and the difference was statistically significant （ all P 〈 0. 05 ）. However, there was no significant difference about K1 ,K2 （ all P 〉 0.05 ）. Moreover, the AL,K1 ,K2 and CCT measured by the two instruments had close linear correlation （all r 〉0.97 ,all P 〈0.01 ）. The Bland- Altman plot showed that 95% LoA （ limits of agreement） of AL was （ -0.057 to 0. 133 ） mm,K1 was （ -0.456 to 0. 369）D,K2 was （ -0. 388 to 0.549）D and CCT was （ -3.483 to 8.016 ） μm. Conclusion Biometric parameters including AL, Kl,/f2, CCT meas- ured by

关 键 词：SW-9000 重复性 一致性 LENSTAR LS900 

分 类 号：R778[医药卫生—眼科]