输血相容性检测试验室内质控品的制备与可行性分析  

Preparation and feasibility analysis of internal quality control products for blood compatibility testing

作　　者：郑妍[1] 王文婷[1] 穆士杰[1] 杨世明[1] 王琛[1] 谢霞[1] 

机构地区：[1]第四军医大学唐都医院输血科,西安710038

出　　处：《临床血液学杂志（输血与检验）》2017年第4期577-581,586,共6页Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)

摘　　要：目的:探讨利用基层输血科现有资源配制输血相容性检测试验室内质控品,建立符合本实验室的质控方法。方法:回顾性分析2015-06-2016-06配制的输血相容性检测室内质控品(ABO血型鉴定、RhD血型鉴定、不规则抗体筛查、交叉配血)的稳定性和均一性,并与商品化室内质控品结果比较,评价自制室内质控品的临床可行性。结果:自制输血相容性检测室内质控品与商品化质控品在批内稳定性及重复性检测、批间检测差异均无统计学意义(P>0.05)。结论:自制输血相容性检测室内质控品批间差小,抗原抗体反应稳定性好,可以满足输血相容性检测室内质量控制的基本要求。Objective：To investigate how to configuration internal quality control products for blood compatibility testing using the indoor existing resources in the grass-roots level quality control division,and establish the method of laboratory quality control.Method：From June 2015 to June 2016 the uniformity and stability of configuration internal quality products（ABO blood type identification,RhD blood type identification,irregular antibody screening and cross matching test）for blood compatibility testing were analyzed,retrospectively,and compared with the results of commercial laboratory quality products,to evaluate clinical feasibility of homemade quality products.Result：Self-made internal quality control products for blood compatibility testing were good correlated with commercial quality products in stability and repeatability test of intra-and inter-assay,there was no obvious difference（P〉0.05）.Conclusion：The self-made blood compatibility testing internal quality control products have small batch-to-batch difference,good stability of antigen-antibody reaction and could satisfy the basic requirement of blood compatibility testing internal quality control.

关 键 词：输血相容性检测 室内质量控制 质控品 均一性 稳定性 

分 类 号：R457.1[医药卫生—治疗学]