1122例孕妇羊水染色体结果分析  

Analysis on amniotic fluid chromosomes of 1112 cases of pregnant women

作　　者：夏蓉 李娇[2] 滕平 周世豪[3] 

机构地区：[1]湖南省常德市妇幼保健院遗传优生科,常德市产前诊断中心,415000 [2]广西壮族自治区妇幼保健院优生遗传门诊,530000 [3]湖南省长沙市妇幼保健院遗传室,410000

出　　处：《中国优生与遗传杂志》2017年第8期46-47,4,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的对高危孕妇行羊水细胞染色体分析,探讨产前诊断和遗传咨询中的问题。方法分析常德市产前诊断中心1122例羊水产前诊断的结果,总结染色体异常与产前诊断指征的联系。结果成功培养1122例孕妇羊水细胞染色体,发现异常核型36例,占所有标本数3.20%,多态核型49例,占所有标本数4.36%。结论对高危指征孕妇行羊水产前诊断是一项很有必要的工作。Objective：To discuss the problems in prenatal diagnosis and genetic counseling by amniotic fluid cell chromosome analysis in pregnant women at high risk. Methods：Prenatal diagnosis results of 1122 cases from the Changde Prenatal Diagnostic Center were analyzed;and the correlation between chromosomal abnormalities and indications of prenatal diagnosis was summarized. Results：1122 cases of amniotic fluid cell chromosome were successfully cultured;36 cases had abnormal karyotype,accounting for 3.20% of all specimens,while 49 cases had polymorphism karyotype,accounting for 4.36% of all specimens. Conclusion：Prenatal diagnosis of amniotic fluid is a necessary work for pregnant women with high-risk indications.

关 键 词：产前诊断 羊水细胞培养 染色体核型分析 

分 类 号：R440[医药卫生—诊断学] R714.5[医药卫生—临床医学]