超声软标记与胎儿染色体异常的关系的回顾性研究  

Study on the relationship between ultrasound soft markers and fetal chromosomal abnormalities

作　　者：李合华[1] 王长云[1] 王婉群[1] 

机构地区：[1]枣阳市第一人民医院血液透析室,湖北枣阳441200

出　　处：《中国优生与遗传杂志》2017年第8期56-57,97,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的研究与评价超声软标记与胎儿染色体异常的关系,为临床胎儿染色体异常检测提供诊断依据。方法本研究内容经医学伦理委员会批准通过。以2015年1月-2016年6月间在我院妇产科收治并进行产前超声检查的12 500例孕妇作为研究对象,应用超声软标记对胎儿进行检测分析,对本组孕妇中超声软标记检出阳性胎儿具体情况以及染色体异常情况进行回顾分析与观察。结果共对12 500例孕妇进行了产前超声检查,检出有超声软标记阳性胎儿共610例,超声软标记阳性发生率为4.88%。心内强回声光点超声软标记构成比为48.36%(295/610),显著高于其他超声软标记构成比,对比差异显著(P<0.05),具有有统计学意义。结论产前超声检查中超声软标记可用于调整胎儿染色体异常基础风险,具有非侵入性的优点,值得临床推广应用。Objective：To study the relationship between ultrasound soft markers and fetal chromosomal abnormalities. Methods：the present study to 2015 ~ 2016 January in June for the observation period,to my courtyard department of gynaecology and obstetrics and 12 500 cases of pregnant women prenatal ultrasonography as the research object,research content after approved by the medical ethics committee. To review and analyze the clinical data of pregnant women,and to explore the relationship between fetal chromosomal abnormalities and fetal chromosomal abnormalities. In this group,the specific situation and the abnormal condition of the positive fetus were analyzed and observed. Results：in this group,12 500 cases of pregnant women were detected by prenatal ultrasound,610 cases were detected with ultrasound soft markers,the positive rate was 4.88%. The proportion of the soft marker of the strong echo spot in the heart was 48.36%（295/610）,which was significantly higher than that of other ultrasound soft markers,and the difference was significant（P 0.05）. Conclusion：ultrasound soft markers in prenatal ultrasound can be used to adjust the basic risk of fetal chromosomal abnormalities,which is non-invasive,it is worth to be promoted to clinical use.

关 键 词：胎儿 染色体异常 超声软标记 关系 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]