1例脑栓塞患者合并肌酶升高及肝损伤的原因分析  

Analysis of a stroke patient with rise of muscle enzyme concentrations and liver injury

作　　者：任金妹[1] 沈毅[1] 谢宁[1] 薛晓红[1] 

机构地区：[1]复旦大学附属中山医院青浦分院,上海201700

出　　处：《上海医药》2017年第17期69-71,共3页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的:对1例脑栓塞患者治疗过程中出现肌酶升高及肝损伤的原因进行讨论,提高临床药师运用专业知识对临床发生不良反应的判断和分析能力。方法:查阅文献,对该病例中发生肌酶升高和肝损伤不良反应的药物相关因素进行分析。结果:阿托伐他汀钙片可能是肌酶升高和肝损伤原因。结论:临床药师需要利用专业知识对药物不良反应进行分析和监护,提高患者用药安全性。Objective： To improve the judgment and analytic ability of clinical pharmacists for adverse drug reactions （ADR） by analysis of the reasons of muscle enzyme concentration rise and liver injury of a case of stroke patient. Methods： The ADR occurred duo to enzyme concentration rise and liver injury related to drugs were judged and analyzed by reviewing the relative literatures. Results： atorvastatin might induce muscle enzyme concentration rise and liver injury. Conclusion： Clinical pharmacists should use their professional knowledge to judge and analyze ADR so as to improve the safety of medication.

关 键 词：肌酶浓度升高 肝损伤 不良反应 

分 类 号：R575[医药卫生—消化系统] R743.33[医药卫生—内科学]