高血压脑出血患者术后实施镇痛镇静治疗的临床效果  

The Clinical Effect of Sedation Analgesia Treatment in Patients with Hypertensive Intracerebral Hemorrhage after Operation

作　　者：陈晓刚[1] 李文玲[2] 王昆鹏[3] 康进生[4] 单雪飞[1] 陈雅辉[1] CHEN Xiao-gang LI Wen-ling WANG Kun-peng et al(Department of Neurosurgery, the Second General Hospital of Fengrun District, Tangshan 063030, Chin)

机构地区：[1]唐山市丰润区第二人民医院神经外科,河北唐山063030 [2]河北医科大学第二医院神经外科,河北石家庄050000 [3]承德医学院附属医院神经外科,河北承德067000 [4]河北省人民医院神经外科,河北石家庄050051

出　　处：《医学与哲学（B）》2017年第7期44-47,共4页Medicine & Philosophy(B)

摘　　要：探讨高血压脑出血术后镇痛镇静治疗的临床疗效。将218例高血压脑出血患者随机分为两组,试验组患者术后应用舒芬太尼+地佐辛+咪达唑仑镇痛镇静,对照组单纯应用咪达唑仑,观察两组治疗效果。试验组患者术后镇静-躁动评分、血压达危险值例数、颅内压监测值、72h的NIHSS值、48h内再出血率、7d病死率、不良反应发生率均明显低于对照组,差异均有统计学意义(P<0.05)。高血压脑出血患者开颅术后应用舒芬太尼+地佐辛+咪达唑仑镇痛镇静,可减少患者术后躁动,稳定血压及颅内压,保护神经功能,降低颅内再出血率、病死率、不良反应发生率,值得临床应用和推广。To study clinical effect of sedation analgesia treatment in patients with hypertensive intracerebral hemorrhage after operation.218 patients with hypertensive cerebral hemorrhage were randomly divided into two groups, Sufentanil＋Dezocine＋Midazolam had been applied to postoperative sedation analgesia treatment in experiment group, the control group used midazolam only, to observe the therapeutic effect of two groups.The sedation-agitation score, the number of patients with dangerous blood pressure, intracranial pressure, national institutes of health stroke scale of postoperative 72h, rebleeding rate within 48h, 7 days＇mortality and adverse reaction of experimental group were all lower than control group, the difference had statistical significance （P〈0.05）.In patients with hypertensive intracerebral hemorrhage after operation, sufentanil＋dezocine＋midazolam could reduce postoperative dysphoria, stabilize postoperative blood pressure and ICP, protect neurological function, meanwhile, reduce the rebleeding rate, mortality and adverse reaction.It is worth clinical application and promotion.

关 键 词：高血压脑出血 镇痛镇静 镇静-躁动评分 再出血率 颅内压 

分 类 号：R743.34[医药卫生—神经病学与精神病学]