垂体泌乳素瘤影像生长方式分类和临床关系的研究  

Study on imaging growth manner and clinical characteristics of pituitary prolactinoma

作　　者：于群[1] 徐硕[1] 陆小明[1] 刘宁[1] 洪汛宁[2] 鲁艾林[1] 

机构地区：[1]南京医科大学第一附属医院神经外科,210029 [2]南京医科大学第一附属医院放射科,210029

出　　处：《临床神经外科杂志》2017年第4期271-274,278,共5页Journal of Clinical Neurosurgery

基　　金：基金项目:江苏省六大人才高峰(WSW-023)

摘　　要：目的对泌乳素瘤的影像学生长方式进行分类,探索其与临床治疗及预后之间的关系。方法选择在我科治疗的168例泌乳素瘤患者(男性60例,女性108例)为研究对象,对其影像学生长方式进行分类,与临床治疗及预后进行对比研究。结果鞍内型(B型)生长多见于低年龄(82.8%,P<0.05)及低泌乳素(76.7%,P<0.05)患者,突破型(A型)及包绕型(C型)生长多见于高年龄(两者合计68.0%,P<0.05)及高泌乳素(两者合计66.2%,P<0.05)患者。结论泌乳素瘤的影像学生长方式会因患者性别、年龄及泌乳素水平变化而发生改变,寻找相互之间的关系对选择合理的治疗方法、探索发病原因及发病机制及改善预后具有一定的参考意义。Objective To classify the imaging growth manner of prolactinoma and explore its relationship between clinical manifestation and the treatment outcome. Methods A total of 168 patients with prolactinoma（ 60 males and 108 females） who were treated in our department were selected as research target. The relationship between the image characteristics,clinical manifestations and the treatment outcome were compared and evaluated. Results Saddle inside-type growth was more common in younger age and low prolactin level patients（ 82. 8%,P 〈0. 05）,breakthrough and surrounded type growth was more common in older age（ total proportion was 68. 0%,P〈 0. 05） and high prolactin level patients（ total proportion was 66. 2%,P〈 0. 05）. Conclusion The imaging growth manner of prolactinoma will change due to changes in gender,age and prolactin levels,the relationship between them can guide us to explore the etiology and pathogenesis,then choose a reasonable treatment to improve the prognosis.

关 键 词：垂体泌乳素瘤 影像学生长方式 性别 年龄 血清泌乳素 

分 类 号：R739.41[医药卫生—肿瘤]