醋酸奥曲肽联合泮托拉唑治疗难治性上消化道出血临床分析  

Clinical Analysis of Octreotide Acetate and Pantoprazole in Treatment of Refractory Upper Gastrointestinal Bleeding

作　　者：臧珺 

机构地区：[1]徐州市矿山医院内三科,江苏徐州221000

出　　处：《中外医疗》2017年第20期116-117,120,共3页China & Foreign Medical Treatment

摘　　要：目的探讨分析醋酸奥曲肽联合泮托拉唑治疗难治性上消化道出血的临床效果。方法方便选取该院2013年2月—2016年6月收治的80例难治性上消化道出血根据治疗方式分组,定义接受泮托拉唑治疗的40例患者作为对照组,另外在此基础上采用醋酸奥曲肽治疗的40例患者作为观察组,观察对比两组患者的治疗效果。结果观察组总有效率为90.0%,明显高于对照组70.0%(P<0.05);观察组止血时间为(42.4±5.5)h,明显短于对照组(68.6±7.8)h(P<0.05);两组患者不良反应发生率对比差异无统计学意义(P>0.05),症状均较轻微,停药后未经处理自行消失。结论醋酸奥曲肽联合泮托拉唑治疗难治性上消化道出血的临床效果显著,值得推广。Objective To discuss and analyze the clinical effect of octreotide acetate and pantoprazole in treatment of refractory upper gastrointestinal bleeding. Methods 80 cases of patients with refractory upper gastrointestinal bleeding admitted and treated in our hospital from February 2013 to June 2016 were convenient selected and divided into two groups according to the treatment method with 40 cases in each, the control group were treated with pantoprazole, while the observation group were treated with octreotide acetate and pantoprazole, and the treatment effect was compared between the two groups. Results The total effective rate in the observation group was obviously higher than that in the control group,(90.0% vs70.0%)(P <0.05), and the hemostasis time in the observation group was obviously shorter than that in the control group[(42.4±5.5)h vs(68.6±7.8)h](P<0.05), and the difference in the incidence rate of adverse reactions between the two groups was not statistically significant(P>0.05), and the symptoms were mild, and disappeared without handling. Conclusion The clinical effect of octreotide acetate and pantoprazole in treatment of refractory upper gastrointestinal bleeding is obvious, which is worth promotion.

关 键 词：醋酸奥曲肽 泮托拉唑 难治性上消化道出血 

分 类 号：R573[医药卫生—消化系统]