经胃镜放置空肠营养管对急性重症胰腺炎的营养支持和细胞免疫功能的影响  

The effect of endoscopic naso-jejunal feeding tube placement on nutrition support and cellular immune function in patients with severe acute pancreatitis

作　　者：习晓丽[1] 

机构地区：[1]四川省宜宾市第一人民医院消化内科,四川宜宾644000

出　　处：《实用医院临床杂志》2017年第5期93-95,共3页Practical Journal of Clinical Medicine

摘　　要：目的探讨经胃镜放置空肠营养管后肠内营养(EN)对改善急性重症胰腺炎(SAP)患者营养状况和细胞免疫功能的影响。方法 2013年1月至2015年12月我院收治的104例SAP患者,按照随机数字表法分为EN组50例和全胃肠外营养(TPN)组54例,EN组患者接受经胃镜放置空肠营养管行早期(<3天)EN治疗,TPN组进行传统TPN治疗,比较两组SAP患者的营养状况、T淋巴细胞亚群的影响。结果两组患者治疗前后体质量指数(BMI)、血清总蛋白和血清白蛋白的变化比较差异有统计学意义(p<0.05);T淋巴细胞亚群治疗后差异均有统计学意义(P<0.05)。结论 EN是SAP营养支持的重要途径,能有效地促进营养状态的恢复,改善免疫功能,与TPN相比具有明显优势,经胃镜放置空肠营养管是实施EN的有效可靠手段。Objective To investigate the effects of enteral nutrition （EN） on nutritional status and cellular immune function in patients with severe acute pancreatitis （SAP） by gastroscopic placement of jejunum nutrition tube. Methods Between January 2013 and December 2015 our hospital treated 104 SAP patients. These patients were randomly divided into EN group （n = 50） and TPN group （n = 54）. The EN group received enteral nutrition （EN） through the naso-jejunal feeding tube and the TPN group received total parenteral nutrition （TPN）. The nutritional status and T lymphocyte subsets were compared between the two groups. Results serum to- tal protein and serum albumin after the treatments were significantly different compared to before treatments （ P 〈 0. 05 ）. The differ- ences in T lymphocyte subsets before and after the treatment were also statistically significant （P 〈 0. 05）. Conclusion EN is an im- portant nutrition support way for SAP patients and can effectively promote the recovery of nutritional status and improve the immune function. The naso-jejunal feeding tube placement through the endoscopy is an effective and reliable means for EN.

关 键 词：急性重症胰腺炎 营养 免疫功能 肠内营养 

分 类 号：R576[医药卫生—消化系统]