直肠癌患者行腹腔镜与开腹直肠癌根治术的近远期疗效对比  

Short term and long-term efficacy of laparoscopic and open radical resection for rectal cancer

作　　者：曾昊[1] 袁波[1] 何茂梁[1] 

机构地区：[1]成都市第六人民医院,四川成都610051

出　　处：《临床医药文献电子杂志》2017年第42期8119-8120,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的分析比较直肠癌患者行腹腔镜与开腹直肠癌根治术的近远期疗效。方法选取2012年5月~2014年3月我院收治的直肠癌患者65例,随机分为实验组和对照组,其中实验组(33例)接受腹腔镜治疗手术,对照组(32例)接受开腹治疗手术,比较2组患者在术中的平均出血量、术后的平均排气时间、住院时间、并发症发生率,以及随访3年后的2组患者的局部发生率、远处转移率、生存率等相关临床指标。结果 2组患者术中的平均出血量、术后的平均排气时间、住院时间、并发症发生率分别为118.4±8.8mL、3.0±0.3d、10.8±2.5d、9.1%;141.6±9.7mL、5.1±0.6d、16.8±3.4d、28.1%,差异有统计学意义(P<0.05),3年的局部发生率、远处转移率、累计生存率分别为9.1%、12.1%、30.3%;12.5%、21.9%、37.5%,差异无统计学意义(P>0.05)。结论 2组患者的远期疗效差异虽无统计学意义(P>0.05),但实验组近期疗效明显优于对照组,差异有统计学意义(P<0.05),说明腹腔镜治疗直肠癌能够降低患者出血量,减少排气及住院时间,由此提高患者的生活质量,具有临床推广价值。Objective To compare the short-term and long-term efficacy of laparoscopic and open radical resection for rectal cancer.Methods 65 patients with rectal cancer from May 2012~2014 year in March in our hospital were randomLy divided into experimental group and control group,the experimental group （33 cases） underwent laparoscopic surgery, the control group （32 cases） received open surgery, compared 2 groups of patients in the intraoperative mean blood loss,mean postoperative exhaust time hospitalization time and incidence rate of complications,and follow-up of 2 groups of patients after 3 years,the local incidence rate,distant metastasis rate,survival rate and other clinical indicators.Results 2 groups of patients with the average amount of bleeding,Postoperative exhaust time,average hospitalization time and incidence of complications were 118.4 ± 8.8mL, 3 ± 0.3 d, 10.8± 2.5d,9.1%; 141.6± 9.7mL and 5.1± 0.6d, 16.8 ± 3.4d,28.1 %,the difference was statistically significant （P〈0.05）,3 the Bureau of the Ministry of the incidence rate,distant metastasis rate and cumulative survival rates were 9.1%,12.1%,30.3%; 12.5%,21.9%,37.5%,the difference was not statistically significant （P〉0.05）. Conclusion Although there was no statistically significant difference in curative effect of 2 groups of patients （P〉0.05）,but the curative effect of experimental group was significantly better than the control group,the difference was statistically significant （P〈0.05）,indicating the laparoscopic treatment of rectal cancer patients can reduce the amount of bleeding,reduce exhaust and hospitalization time, thus improve the quality of life of patients,which has clinical value.

关 键 词：直肠癌 腹腔镜 开腹根治术 近远期疗效 

分 类 号：R735.37[医药卫生—肿瘤]