清热豁痰通腑方治疗脑出血急性期痰热腑实证临床观察  

Clinical Observation of Qingre Huotan Tongfu Prescription for Cerebral Hemorrhage in Acute Stage of Phlegm-Heat FU-Organ Sthenia Syndrome

作　　者：雷小宁 乔路敏 

机构地区：[1]银川市中医医院急诊科,宁夏银川750001

出　　处：《新中医》2017年第9期24-27,共4页New Chinese Medicine

基　　金：宁夏回族自治区自然科学基金项目(NZ10189)

摘　　要：目的:观察清热豁痰通腑方治疗脑出血急性期痰热腑实证的有效性和安全性。方法:将100例脑出血急性期痰热腑实证患者按随机数字表法分为治疗组和对照组各50例,2组均接受西医内科基础治疗,治疗组加用清热豁痰通腑方治疗,2组均治疗28天。在治疗前、治疗第7天、第28天分别行头颅CT检查,观察出血量变化情况;在治疗前、治疗第28天分别采用美国国立卫生研究院卒中量表(NIHSS)、脑卒中专门生存质量量表(SS-QOL)对患者的神经功能缺损情况及生活质量进行评价,并对治疗的安全性进行评定。结果:治疗后,治疗组总有效率87.23%,对照组总有效率72.92%,2组比较,差异无统计学意义(P>0.05)。治疗组治疗第7天、第28天与治疗前相比,出血量均有减少,差异均有统计学意义(P<0.05);治疗第28天,治疗组的血肿吸收情况优于对照组,差异有统计学意义(P<0.05)。与治疗前相比,2组治疗第28天的NIHSS评分均降低(P<0.05);2组治疗前后NIHSS评分差值比较,差异有统计学意义(P<0.05)。2组治疗第28天的SS-QOL评分与治疗前比较均提高,差异均有统计学意义(P<0.05)。治疗第28天,治疗组SS-QOL评分高于对照组,差异有统计学意义(P<0.05)。结论:在内科治疗的基础上加用清热豁痰通腑方治疗脑出血急性期痰热腑实证患者可促进血肿吸收,改善神经功能缺损情况,提高患者的生存质量,且无明显不良反应,在脑出血的临床治疗中发挥了一定的优势作用。Objective： To observe the effectiveness and safety of Qingre Huotan Tongfu prescription in treating patients with cerebral hemorrhage in acute stage of phbegm-heat Tll-organ sthenia syndrome. Methods： Divided 100 cases of patients with cerebral hemorrhage in acute stage of phlegm-heat FU-organ sthenia syndrome into the treatment group and the control group,according to the random table method, 50 cases in each group. The two groups both received internal medical treatment of western medicine, while the treatment group was given Qingre Huotan Tongfu prescription additionally. Both groups received treatment for 28 days. Skull CT examination was conducted before treatment, in the 7th day and 28 th day of treatment so as to observe bleeding; NIH stroke scale（NIHSS） and Stroke specific quality of life scale（ss-qol） were adopted to evaluated neurological deficit and quality of life before and after treatment, and evaluated safety of the treatment. Results： The total effective rate was 87.23% in the treatment group, and was 72.92% in the control group, there was no significant difference（P〈0.05）. The volume of cerebral hemorrhage of the treatment group in the 7th day and the 28 th day of treatment were less than those before treatment（P〈0.05）. Hematoma absorption of the treatment group in the 28 th day of treatment was better than that of the control group, the difference being significant（P〈0.05）. NIHSS scores of both groups in the 28 th day of treatment were lower than those before treatment, and there were significant differences in the NIHSS scores between the two groups after treatment（P〈0.05）. SS-QOL scores of both groups in the 28 th day of treatment were higher than those before treatment（P〈0.05）, and the scores of the treatment group were higher than those of the control group, the difference being significant（P〈0.05）. Conclusion： Based on internal medical treatment, application of Qingre Huotan Tongfu prescription can promote hematoma absorption, improve neur

关 键 词：脑出血 急性期 痰热腑实证 中西医结合疗法 清热豁痰通腑方 出血量 神经功能 生存质量 

分 类 号：R743.3[医药卫生—神经病学与精神病学]