酒依赖患者复饮与生化指标关系研究  

Study on the Relationship between Re-drink and Biochemical Indexes of Wine Dependent Patients

作　　者：王凤[1] 何英[1] 

机构地区：[1]四川大学华西医院心理卫生中心,四川成都610041

出　　处：《四川医学》2017年第9期1025-1027,共3页Sichuan Medical Journal

摘　　要：目的了解酒依赖患者复饮对其血液生化指标的影响,为评估复饮对患者身体健康的影响提供客观依据。方法采用贝克曼全自动生化分析仪对符合ICD-10诊断标准的167例酒依赖患者进行生化项目检测分析,根据其首次入院及再次入院情况将患者分为初次戒酒组和复饮组,对两组患者血清电解质、血清酶及其他血清生化指标进行分析。结果 (1)电解质改变,复饮组较初次戒酒组血钾降低,差异有统计学意义(P<0.05)。(2)血清酶改变,复饮组较初次戒酒组低血清天冬氨酸转氨酶(AST)、谷氨酰转肽酶(GGT)指标升高,差异有统计学意义(P<0.05)。(3)其他血清生化指标改变,复饮组较初次戒酒组尿酸升高,白蛋白(ALB)降低,差异有统计学意义(P<0.05)。结论酒依赖患者复饮组的生化指标与初次入院者相较会发生相应改变,对患者身体健康造成明显损害,应大力宣传反复饮酒的危害和酒依赖的防治知识,对酒依赖的患者应进行尽可能的彻底戒断。Objective To study the effect of re-drink on blood biochemical in dicators of wine dependent patientsand to provide an objective basis for assessing the effect of re-drink on patients＇ physical health. Methods The biochemical indicators of 167alcohol-dependent patients who met ICD-10 diagnostic criteria were analyzed by Beckman automatic biochemical analyzer. The patients were divided into the first-quit group and the re-drink group according to their first admission and re-admission. Serum electrolytes,serum enzymes and other serum biochemical markers were analyzed in both groups. Results ①Compared with the first-quit group ,the serum potassium decreased in the re-drink group,the difference was statistically significant（ P 〈0. 05 ）. ②The serum levels of aspartate arninotransferase（AST） and glutamyhransferase（GGT） in the re-drink group were significantly higher than those in the first-quit group（ P 〈 0. 05 ）. ②The other serum biochemical indexes, uric acid of the re-drink group was higher than that in the first-quit group, and the albumin （ALB）was lower than the first-qult group, the difference was statistically significant （P 〈 0. 05 ）. Conclusion The biochemical indicators of alcohol-dependent patients in the re-drink group signifieantly changed compared with those of the first-quit patients, and the health of the patients was significantly damaged. The harm of repeated drinking and the prevention and control of alcohol dependence should be vigorously promoted as soon as possible.

关 键 词：酒依赖 复饮 生化指标 

分 类 号：R749.62[医药卫生—神经病学与精神病学]