同步放化疗和三维适形放疗对局部晚期非小细胞肺癌患者生存率的影响及安全性比较  

Effect of concurrent chemoradiotherapy and three-dimensional conformal radiotherapy on survival rate and safety of locally advanced non-small cell lung cancer

作　　者：李波[1] 

机构地区：[1]山西省肿瘤医院放胸二病区,太原030013

出　　处：《中国实用医刊》2017年第17期57-59,共3页Chinese Journal of Practical Medicine

摘　　要：目的 比较同步放化疗和三维适形放疗对局部晚期非小细胞肺癌（NSCLC）生存率的影响及安全性。 方法 选取NSCLC患者48例，根据治疗方式的不同分为对照组与研究组。对照组予以三维适形放疗治疗，研究组予以同步放化疗，对比两组患者的生存率及不良反应发生情况。 结果 研究组生存率（52.4%）明显高于对照组（28.6%，P〈0.05），不良反应多于对照组（P〈0.05）。 结论 同步放化疗治疗无法耐受手术的NSCLC患者近期效果较好，虽然不良反应较多，但患者均能耐受。Objective To compare the effects of concurrent chemotherapy and three-dimensional conformal radiotherapy on survival rate and safety of locally advanced non-small cell lung cancer （NSCLC） patients. Methods Forty- eight NSCLC patients were divided into control group and study grnup according to the different treatments. Patients in the control group were treated by three-dimensional conformal radiother- apy treatment, and patients in the study group were treated by radiotherapy and chemotherapy, the survival rate and adverse reactions of the two groups were compared. Resldts The survival rate of the study group （52. 4% ） was significantly higher than that of the control group （28. 6%, P 〈0. 05）, while the incidence of adverse reactions in the study group was significantly higher than that in the control group （P 〈 0〈 05 ）. Conclusions The short term effect of concurrent chemo - radiotherapy on NSCLC patients who cannot tolerate surgery is better. Although there are more adverse reactions, those can be tolerated.

关 键 词：同步放化疗 三维适形放疗 局部晚期非小细胞肺癌 生存率 安全性 

分 类 号：R734.2[医药卫生—肿瘤]