Influence of corneal power on circumpapillary retinal nerve fiber layer and optic nerve head measurements by spectral-domain optical coherence tomography  

作　　者：Kazunori Hirasawa Nobuyuki Shoji 

机构地区：[1]Department of Orthoptics and Visual Science,School of Allied Health Sciences,Kitasato University,Sagamihara,Kanagawa 252-0373,Japan [2]Department of Ophthalmology,School of medicine,Kitasato University,Sagamihara,Kanagawa 252-0373,Japan

出　　处：《International Journal of Ophthalmology(English edition)》2017年第9期1385-1391,共7页国际眼科杂志（英文版）

基　　金：Supported by a Research Fund at Kitasato University

摘　　要：AIM：To evaluate the influence of corneal power on circumpapillary retinal nerve fiber layer（cp RNFL）and optic nerve head（ONH）measurements by spectral-domain optical coherence tomography（SD-OCT）.METHODS：Twenty-five eyes of 25 healthy participants（mean age 23.6±3.6y）were imaged by SD-OCT using horizontal raster scans.Disposable soft contact lenses of different powers（from-11 to＋5 diopters including 0diopter）were worn to induce 2-diopter changes in corneal power.Differences in the cp RNFL and ONH measurements per diopter of change in corneal power were analyzed.RESULTS：As corneal power increased by 1 diopter,total and quadrant cp RNFL thicknesses,except for the nasal sector,decreased by-0.19 to-0.32μm（P〈0.01）.Furthermore,the disc,cup,and rim areas decreased by-0.017,-0.007,and-0.015 mm2,respectively（P〈0.001）;the cup and rim volumes decreased by-0.0013 and-0.006 mm3,respectively（P〈0.01）;and the vertical and horizontal disc diameters decreased by-0.006 and-0.007 mm,respectively（P〈0.001）.CONCLUSION：For more precise OCT imaging,the ocular magnification should be corrected by considering both the axial length and corneal power.However,the effect of corneal power changes on cp RNFL thickness and ONH topography are small when compare with those of the axial length.AIM：To evaluate the influence of corneal power on circumpapillary retinal nerve fiber layer（cp RNFL）and optic nerve head（ONH）measurements by spectral-domain optical coherence tomography（SD-OCT）.METHODS：Twenty-five eyes of 25 healthy participants（mean age 23.6±3.6y）were imaged by SD-OCT using horizontal raster scans.Disposable soft contact lenses of different powers（from-11 to＋5 diopters including 0diopter）were worn to induce 2-diopter changes in corneal power.Differences in the cp RNFL and ONH measurements per diopter of change in corneal power were analyzed.RESULTS：As corneal power increased by 1 diopter,total and quadrant cp RNFL thicknesses,except for the nasal sector,decreased by-0.19 to-0.32μm（P〈0.01）.Furthermore,the disc,cup,and rim areas decreased by-0.017,-0.007,and-0.015 mm2,respectively（P〈0.001）;the cup and rim volumes decreased by-0.0013 and-0.006 mm3,respectively（P〈0.01）;and the vertical and horizontal disc diameters decreased by-0.006 and-0.007 mm,respectively（P〈0.001）.CONCLUSION：For more precise OCT imaging,the ocular magnification should be corrected by considering both the axial length and corneal power.However,the effect of corneal power changes on cp RNFL thickness and ONH topography are small when compare with those of the axial length.

关 键 词：optical coherence tomography ocularmagnification corneal power circumpapillary retinal nervefiber layer optic nerve head 

分 类 号：R770.4[医药卫生—眼科]