术后调强放疗对宫颈癌患者卵巢功能的影响  

Influence of postoperative IMRT on the ovarian function of patients with cervical cancer

作　　者：鲍慧 孙晓东[1] 王明 贺晶[3] 

机构地区：[1]延安大学附属医院肿瘤科二病区,陕西延安716000 [2]威海市中心医院肿瘤科,山东威海264400 [3]延安大学附属医院妇产科,陕西延安716000

出　　处：《中国性科学》2017年第9期80-83,共4页Chinese Journal of Human Sexuality

摘　　要：目的:探讨术后调强放疗对宫颈癌患者卵巢功能的影响。方法:选取我院2012年10月至2015年10月收治的宫颈癌患者81例,依据随机数字表法将这些患者分为调强放疗组(n=41)和常规放疗组(n=40)两组,对两组患者的卵巢功能、毒副反应发生情况、2年和3年复发情况及复发时间、死亡情况进行统计分析。结果:调强放疗组患者的E2、P、FSH水平均显著低于常规放疗组(P<0.05),LH水平显著高于常规放疗组(P<0.05),调强放疗组患者的骨髓抑制、消化系统反应、放射性膀胱炎发生率19.5%、24.4%、9.8%均显著低于常规放疗组的47.5%、55.0%、25.0%(P<0.05)。结论:术后调强放疗能够有效保护宫颈癌患者的卵巢功能。Objectives： To investigate the influence of postoperative IMRT on the ovarian function of patients with cervical cancer. Methods： 81 cervical cancer patients who were treated in our hospital from Oct. 2012 to Oct. 2015 were selected. These patients were divided into IMRT group （ n = 41 ） and conventional radiotherapy group （ n = 40）. The ovarian function, incidence of side effects, 2 - year recurrence, 3 - year recurrence, times of recurrence and number of death in the two groups were statistically analyzed. Results ： The E2, P, FSH levels of IMRT group were significantly lower （ P 〈 0. 05 ）. The LH level of IMRT group was significantly higher （ P 〈 0. 05）. The bone marrow suppression, digestion system response, radiation cystitis incidences were 19.5% （8/ 41 ）, 24.4% （ 10/41 ） and 9.8% （4/41） , which were significantly lower than these of conventional radiotherapy group （ P 〈 0.05）. Conclusion： Postoperative IMRT can effectively protect ovarian function of patients with cervi- cal eancer.

关 键 词：术后调强放疗 宫颈癌 卵巢功能 影响 

分 类 号：R737.33[医药卫生—肿瘤]