美沙酮维持治疗海洛因依赖患者的孤独感与疼痛的相互关系  

Reciprocal relationship between loneliness and pain among heroin-dependent patients receiving methadone maintenance treatment

作　　者：包黎[1] 钟宝亮[1] 李毅 朱军红[1] 

机构地区：[1]华中科技大学同济医学院附属武汉精神卫生中心/第九临床学院精神科,武汉430012

出　　处：《安徽医科大学学报》2017年第10期1513-1516,共4页Acta Universitatis Medicinalis Anhui

基　　金：国家自然科学基金青年基金(编号:30800364);米尔斯坦亚美医学基金会研究项目资助;武汉市卫生和计划生育委员会资助课题(编号:WG16A02)

摘　　要：目的分析美沙酮维持治疗(MMT)海洛因依赖患者(HDPs)的孤独感与疼痛的相互关系。方法 603例MMT门诊HDPs完成一般情况问卷、抑郁自评量表、焦虑自评量表、单一条目孤独感自评问卷和五点口述分级评分疼痛强度自评问题。用有序因变量Logistic回归分析孤独感与疼痛的双向联系。结果孤独感与疼痛强度评分呈中度显著正相关性(r=0.453,P<0.001)。控制社会人口学因素、物质使用特征变量、抑郁症状和焦虑症状的潜在混杂效应后,疼痛强度增加与孤独感风险上升呈显著相关性(OR=1.53,P<0.001),孤独感水平升高也与疼痛强度增加呈显著相关性(OR=1.22,P<0.042)。结论 MMT门诊HDPs的孤独感与疼痛存在双向作用,社会心理干预配合合适的疼痛管理有利于HDPs的全面康复。Objective To examine the reciprocal relationship between loneliness and pain among heroin-dependent patients （HDPs） receiving methadone maintenance treatment （MMT）. Methods A total of 603 MMT HDPs comple- ted a general information questionnaire, self-rating depression scale, self-rating anxiety scale, one sing-item loneli- ness self-rating scale and 5-point verbal rating scale for pain intensity. Ordinal Logistic regression was used to as- sess the reciprocity between loneliness and pain. Results Loneliness score was significantly and moderately correla- ted with pain intensity score（ r = 0. 453, P 〈 0. 001 ）. After controlling for the potential confounding effects of de- mographic factors, substance use characteristics, depression and anxiety, increased pain intensity was significantly associated with increased risk for loneliness（ OR = 1.53, P 〈0. 001 ） and increased level in loneliness was signifi- cantly associated with increased pain intensity （ OR = 1.22, P 〈 O. 042 ）. Conclusion There is a bidirectional effect between loneliness and pain among MMT HDPs. A psychosocial intervention adjunct to appropriate pain man- agement is helpful for the rehabilitation of HDPs.

关 键 词：美沙酮维持治疗 海洛因依赖 孤独感 疼痛 相互 关系 

分 类 号：R749.99[医药卫生—神经病学与精神病学]