鼻部横纹肌肉瘤诊疗分析  

Clinical analysis of nose rhabdomyosarcoma

作　　者：李克鹏[1] 刘柱[1] 金书丞 金红军[1] 张玉杰[1] 

机构地区：[1]郑州大学第一附属医院鼻科,郑州450052 [2]兰州大学第二临床学院

出　　处：《临床耳鼻咽喉头颈外科杂志》2017年第18期1398-1401,1407,共5页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:提高对发生于鼻部的横纹肌肉瘤的认识。方法:回顾性分析24例鼻部横纹肌肉瘤患者的临床资料。结果:鼻部横纹肌肉瘤胚胎型多见,临床分期:Ⅰ期3例,Ⅱ期4例,Ⅲ期11例,Ⅳ期6例。治疗方法以手术切除+放疗+多周期化疗的综合治疗为主。患者预后较差。1年生存率为70.8%(17/24),3年生存率为30.3%(8/24)。结论:对不同的患者需采取不同的手术方案,并辅以术后放化疗。通过多学科的共同配合,可延长患者的生存时间。Objective：To improve the diagnosis of the nose rhabdomyosarcoma.Method：Twenty-four patients with nose rhabdomyosarcoma were studied retrospectively.Result：Among 24 patients with nose rhabdomyosarcoma,three patients were in stageⅠ,four patients were in stageⅡ,eleven patients were in stage Ⅲ,and six patients were in stage Ⅳ.Embryonal rhabdomyosarcoma is the commonest in all the pathological types.Most patients need comprehensive therapy,including surgery operation,radiotherapy,and multicycle chemotherapy.Prognosis was poor in most of the cases.The survival rate of one year was 70.8%（17/24）,and survival rate of three years was 30.3%（8/24）.Conclusion：Different surgical protocols should be adopted for different patients,and postoperative chemoradiotherapy should be adopted for advanced treatment.By means of multidisciplinary collaboration,the patient′s survival time would be prolonged.

关 键 词：横纹肌肉瘤 鼻肿瘤 治疗 

分 类 号：R739.62[医药卫生—肿瘤]