肺癌患者电视胸腔镜手术后咳嗽的影响因素分析:单中心前瞻性研究  

Influencing factors of postoperative cough after lung resection in patients with lung cancer by video-assisted thoracic surgery:a single centre prospective study

作　　者：林嵘嘉 车国卫[1] 徐志华[1] 王明铭[1] 李鹏飞[1] 杨梅[1] 

机构地区：[1]四川大学华西医院胸外科,成都610041

出　　处：《中国胸心血管外科临床杂志》2017年第10期748-752,共5页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：四川省科技厅基金项目(2015SZ0158)

摘　　要：目的探讨影响肺癌患者术后咳嗽的因素。方法 2016年2月至2017年2月,应用中文版莱斯特咳嗽量表(Mandarin Chinese version of the Leicester Cough Questionnaire,LCQ-MC)问卷调查四川大学华西医院胸外科单个医疗组130例行胸腔镜肺癌手术的患者,其中男65例、女65例,平均年龄(58.75±9.34)岁。术前及术后LCQ-MC问卷调查,分析LCQ-MC值,克朗巴赫(Cronbachα)系数及影响因素。结果咳嗽组LCQ-MC生理维度值显著低于无咳嗽组,差异有统计学意义(6.30±0.76 vs.6.56±0.60,P=0.044),而两组术前LCQ-MC值总分差异无统计学意义(19.53±1.78 vs.20.03±1.45,P=0.080)。咳嗽组术后LCQ-MC值显著低于无咳嗽组,差异有统计学意义(17.32±2.79 vs.19.70±1.39,P=0.001),且术后咳嗽组LCQ-MC值在生理,心理和社会方面(5.32±1.14,5.73±1.14,6.23±0.88)均显著低于无咳嗽组(6.25±0.63,6.67±0.54,6.78±0.49,P=0.001,P=0.001,P=0.001),差异均有统计学意义。logistic多因素分析表明肺癌患者术后出现咳嗽症状的相关危险因素分别是术前咳嗽(OR=0.354,95%CI 0.126~0.994,P=0.049)和麻醉时间长(OR=1.021,95%CI 1.003~1.040,P=0.021)。结论肺癌患者术后出现咳嗽症状的危险因素是术前有咳嗽症状及麻醉时间长。Objective To explore the factors of postoperative cough in lung cancer patients. Methods Totally 130 lung cancer patients of single medical team （average age of 58.75±9.34 years, 65 males and 65 females）, from February 2016 to February 2017 in the Department of Thoracic Surgery of West China Hospital of Sichuan University, were investigated by Mandarin Chinese version of the Leicester Cough Questionnaire （LCQ-MC）. We analyzed and calculated the preoperative and postoperative scores of LCQ-MC, Cronbach ct and the influencing factor. Results The preoperative score of LCQ-MC＇s physiological dimension was significantly lower in the postoperative cough group （6.30±0.76） than that of the postoperative non-cough group （6.56±0.60, P=0.044）, while the preoperative total score of LCQ-MC （19.53±1.78, 20.03± 1.45） was not statistically different （P=0.080）. The postoperative score of LCQ-MC was significantly lower in the postoperative cough group （17.32±2.79） than that of the postoperative non-cough group （19.70±1.39, P〈0.001）. And the scores of physiological, psychological and social dimension were significantly lower in the postoperative cough group （5.32 ±1.14, 5.73±1.14, 6.23±0.89） than those of the postoperative non-cough group （6.25±0.63, 6.67±0.54, 6.78±0.49） （P values were all less than 0.001）. The result of multi-factor logistic regression analysis showed the condition of preoperative cough symptom （0R=0.354, 95%CI=0.126-0.994, P=0.049） and anesthesia time （OR=1.021, 95% CI=1.003-1.040, P=0.021） were the risk factors. Conclusion The risk factors of postoperative cough symptoms in lung cancer patients are the condition of preoperative cough symptoms and anesthesia time.

关 键 词：影响因素 胸腔镜肺手术 咳嗽 肺癌 

分 类 号：R734.2[医药卫生—肿瘤]