CXCR3和P120ctn与乳腺癌关系的研究进展  

The progress of research on expression and significance of CXCR3 and P120ctn in breast cancer

作　　者：王永胜 王迎宾 

机构地区：[1]山西医科大学,太原030001

出　　处：《中国临床新医学》2017年第8期820-824,共5页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：乳腺癌是女性排名第一的恶性肿瘤,乳腺癌易发生侵袭转移,严重危害女性健康。随着分子生物学研究领域的快速发展,人们对乳腺癌发生及演进机制的了解不断深入,乳腺癌的分子生物学发病机制和预后因素的探讨已成为目前研究的热点。其中趋化因子受体3(CXC-chemokine receptor3,CXCR3)和P120连环蛋白(P120ctn)与肿瘤的发生、发展、侵袭、恶变有一定关系。该文就这两者与乳腺癌关系的研究概况作一综述。Breast cancer lists the first malignant tumor in women and is prone to invasion and metastasis, which dose great harm to women＇s health. With the rapid development of the field of molecular biology, understand- ing of the mechanism of the occurrence and evolution of breast cancer have been deepening. The study of molecular biology and prognostic factors of breast cancer is becoming a hot topic. The chemokine receptor 3 （ CXC-chemokine receptor3, CXCR3） and P120 catenin（P120ctn） are related to the occurrence, development, invasion and cancera- tion of the tumor. The progress of research on the relationship between CXCR3, P120ctn and the development of breast cancer is reviewed in this paper.

关 键 词：乳腺癌 趋化生长因子受体3 P120连环蛋白 

分 类 号：R737.9[医药卫生—肿瘤]