左炔诺孕酮宫内释放系统和常规药物在子宫内膜息肉电切术后预防复发中的应用效果  

Application of Mirena and conventional drugs in preventing recurrence of endometrial polyps

作　　者：张书莲[1] 夏劲[1] 李涛[1] 

机构地区：[1]江西省妇幼保健院妇产科,江西南昌330000

出　　处：《中国当代医药》2017年第27期43-45,共3页China Modern Medicine

基　　金：江西省卫生计生委科技计划项目(20175442)

摘　　要：目的分析左炔诺孕酮宫内释放系统(曼月乐)和常规药物在宫腔镜下子宫内膜息肉电切术后的应用效果。方法选择2013年3月~2015年3月我院收治的子宫内膜息肉患者108例为研究对象,随机分成观察组和对照组,每组54例。观察组行宫腔镜下子宫内膜息肉电切术后+曼月乐治疗方案,对照组行宫腔镜下子宫内膜息肉切除+优思明治疗方案,观察并记录两组患者的各项指标。结果观察组治疗后1、6、12、24个月子宫内膜厚度均低于对照组(P<0.05);观察组治疗后1、6、12、24个月的月经量PBAC评分均高于对照组,差异均有统计学意义(P<0.05)。结论子宫内膜息肉切除术后给予患者曼月乐,可有效降低子宫内膜息肉复发风险,减少不良反应的发生,临床价值良好。Objective To analyze the application effect of Levonorgestrel-releasing intrauterine system Mirena and con- ventional drugs after hysteroseopic endometrial polypectomy.Methods A total of 108 patients with endometrial polyps treated in our hospital from March 2013 to March 2015 were selected as research objects.They were evenly divided into observation group and control group in random.In the observation group,the therapeutic regimen of hysteroscopic en- dometrial polypectomy plus Mirena was applied,while in the control group,the treatment scheme of hysteroscopic en- dometrial polypectomy plus Yasmin was used.The indexes in the two groups were observed and recorded.Results In the observation group,the endometrial thickness 1,6,12 and 24 months after operation was all thinner than those in the con- trol group （P〈0.05）.The PBAC scores of menses 1,6,12 and 24 months after operation in the observation group were all higher than those in the control group （P〈0.05）.Conclusion After endometrial polypectomy,application of Mirena （lev- onorgestrel-releasing intrauterine system） can effective decrease the risk of recurrence of endometrial polyps as well as adverse reactions in a good clinical value.

关 键 词：左炔诺孕酮宫内释放系统 子宫内膜息肉 复发率 安全性 

分 类 号：R737.33[医药卫生—肿瘤]