不同亚型功能性消化不良患者的社会心理特征比较  

Comparison of social psychological characteristics .of patients with different subtypes of functional dyspepsia

作　　者：郑晓人 吴文昭[2] 刘南华[2] 欧阳爱桂[2] 高镇松[3] 王增珍[1] Zheng Xiaoren Wu Wenzhao Liu Nanhua Ou yang Aigui Gao Zhensong Wang Zengzhen(The School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Chin)

机构地区：[1]华中科技大学同济医学院公共卫生学院,武汉430030 [2]汕头市第四人民医院综合科 [3]汕头市第四人民医院精神科 [4]汕头市第四人民医院综合内科

出　　处：《中华消化杂志》2017年第9期607-611,共5页Chinese Journal of Digestion

摘　　要：的分析不同亚型功能性消化不良（FD）患者社会心理特征的差异。 方法纳入2011年8月至2015年7月就诊的210例符合罗马Ⅲ标准的FD患者，分成单纯餐后不适综合征（PDS）组（69例）、单纯上腹痛综合征（EPS）组（74例）和PDS重叠EPS组（67例），采用汉密尔顿抑郁量表（HAMD）、汉密尔顿焦虑量表（HAMA）、生活事件量表（LES）和艾森克人格问卷（EPQ）进行评估分析。统计学方法采用卡方检验和最小显著性差异法。 结果PDS重叠EPS组抑郁和焦虑发生率均为100.0%（67/67），高于单纯PDS组的84.1%（58/69）和91.3%（63/69），差异均有统计学意义（χ2＝11.62、16.34，P均〈0.01）；也高于单纯EPS组的78.4%（58/74）和90.5%（67/74），差异均有统计学意义（χ2＝6.10、6.67，P均〈0.05）。PDS重叠EPS组的躯体焦虑评分和精神焦虑评分分别为（16.34±3.70）和（14.18±2.99）分，高于单纯PDS组的（11.26±3.42）和（10.70±2.94）分，也高于单纯EPS组的（12.30±4.29）和（10.36±2.63）分，差异均有统计学意义（t＝8.33、5.97，6.85、8.06，P均〈0.01）。3组生活事件发生频率居于前两位的都是睡眠习惯改变[67.6%（142/210）]和严重疾病外伤[26.7%（56/210）]。单纯PDS组睡眠习惯改变发生率为53.6%（37/69），低于单纯EPS组的77.0%（57/74）和PDS重叠EPS组的71.6%（48/67），差异均有统计学意义（χ2＝8.68、4.71，P均〈0.05）。单纯PDS组、单纯EPS组和PDS重叠EPS组的P量表评分均以正常居多，E和L量表评分均以偏低居多；单纯PDS组的N量表评分以偏低居多，单纯EPS组和PDS重叠EPS组以正常居多。 结论PDS重叠EPS患者抑郁和焦虑的发生率最高。PDS重叠EPS和单纯EPS患者的躯体焦虑比精神焦虑更明显，都有较多的睡眠事件；单纯PDS患者以情绪反应慢最多见。ObjectiveTo analyze the differences in social psychological characteristics of patients with different subtypes of functional dyspepsia （FD）.MethodsFrom August 2011 to July 2015, 210 FD patients met Rome Ⅲ criteria were enrolled and divided into pure postprandial distress syndrome （PDS） group （69 cases）, pure epigastric pain syndrome （EPS） group （74 cases） and PDS overlap EPS （PDS＋ EPS） group （67 cases）. Hamilton depression scale （HAMD）, Hamilton anxiety scale （HAMA）, life event scale （LES） and Eysenck′s personality questionnaire （EPQ） were used for evaluation.Chi-square test and least-significant difference were performed for statistical analysis.ResultsIncidence rates of depression and anxiety of PDS＋ EPS group were both 100.0% （67/67）, which were higher than those of pure PDS group （84.1%, 58/69 and 91.3%, 63/69）, and the differences were statistically significant （χ2=11.62 and 16.34, both P〈0.01）; which were also higher than those of pure EPS group （78.4%, 58/74 and 90.5%, 67/74）, and the differences were statistically significant （χ2 =6.10 and 6.67, both P〈0.05）. Somatic anxiety score and mental anxiety score of PDS＋ EPS group were 16.34±3.70 and 14.18±2.99, respectively; which were higher than those of pure PDS group （11.26±3.42 and 10.70±2.94） and pure EPS group （12.30±4.29 and 10.36±2.63）, and the differences were statistically significant （t=8.33, 5.97, 6.85 and 8.06; all P〈0.01）. The top two life events in three groups were sleeping habits alteration （67.6%, 142/210） and severe disease or trauma （26.7%, 56/210）. The incidence rate of sleeping habits alteration in pure PDS group was 53.6% （37/69）, which was lower than that in pure EPS group （77.0%, 57/74） and PDS＋ EPS group （71.6%, 48/67）, and the differences were statistically significant （χ2=8.68 and 4.71, both P〈0.05）. Most of P scale scores of pure PDS group, pure EPS group and PDS＋ EPS group were normal, most of E and L

关 键 词：功能性消化不良 亚型 社会心理特征 比较 

分 类 号：R57[医药卫生—消化系统]