Studies on the Activities of Electrophilic Sites on Benzene Ring of 4-Substituted Anilines and Their Acyl Compounds with Multiphilicity Descriptor  

作　　者：SHEN Xizhou HE Huajun YANG Bowen ZHAO Zhigang SHAO Kaiyuan HU Wenxiang 

机构地区：[1]School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430070, P. R. China [2]College of Chemistry and Environment Protection Engineering, Southwest University for Nationalities, Chengdu 610041, R R. China [3]Jingdong Xianghu Laboratory of Beij'ing Excalibur Space, Military Academy of Medical Sciences, Beij'ing 101601, P. R. China [4]Food and Drugs Inspection & Testing Center of Jingning County, Jingning 323500, P. R. China

出　　处：《Chemical Research in Chinese Universities》2017年第5期773-778,共6页高等学校化学研究（英文版）

摘　　要：In this paper, the activities of electrophilic sites on benzene ring of 4-substituted anilines and their acyl compounds were studied with the quantitative indicator of multiphilicity descriptor. Four substituents were synthe- sized with microwave irradiation in good yields to verify the quantitative analysis data. Friedel-Crafts acylation was carried out by the microwave method for the first time.In this paper, the activities of electrophilic sites on benzene ring of 4-substituted anilines and their acyl compounds were studied with the quantitative indicator of multiphilicity descriptor. Four substituents were synthe- sized with microwave irradiation in good yields to verify the quantitative analysis data. Friedel-Crafts acylation was carried out by the microwave method for the first time.

关 键 词：Quantum chemical calculation Electrophilic site Multiphilicity descriptor BENZODIAZEPINE Electrophilic substitution reaction 

分 类 号：TQ085.4[化学工程] TQ655