相关期刊:《Journal of Pharmaceutical Analysis》《Advances in Bioscience and Biotechnology》《Journal of Behavioral and Brain Science》《Journal of Biosciences and Medicines》更多>>
This manuscript explores the potential use of Remimazolam in the intensive care unit(ICU)and critical care units,considering its pharmacological characteristics,clinical applications,advantages,and comparative effecti...
supported by the Scientific Research Project of the Department of Education of Liaoning Province,China(Grant No.:ZF2019036).
Benzodiazepines(BDZs)are used in clinics for anxiolysis,anticonvulsants,sedative hypnosis,and muscle relaxation.They have high consumptions worldwide because of their easy availability and potential addiction.They are...
Benzodiazepines and other benzodiazepine receptor agonists, such as the “Z” drugs, are widely prescribed medications mainly used for treating anxiety and seizures, and for inducing sedation. Unfortunately, despite t...
Kunming Health Personnel Training Project[2020-SW(hou bei)-125];Health Research of Kunming City Health Commission Project(2021-03-09-001).
Alcohol withdrawal syndrome(AWS)is a serious disorder affecting alcohol-dependent patients who abruptly stop or reduce their drinking.Mild or moderate AWS usually appears within 6 to 24 h after the last drink,and symp...
Alcohol withdrawal syndrome(AWS)refers to a series of symptoms and signs that chronic al-coholics experience when they suddenly stop drinking or reduce their drinking,usually 12 to 24 h later.These in-clude tremors,fa...
Background: Hydrolysis improves the sensitivity of drug detection for drug classes such as opiates/opioids and benzodiazepines, which are highly metabolized by glucuronidation and sulfation and should...
Institutional funding from Beijing Institute of Pharmacology and Toxicology。
OBJECTIVE To identify benzodi⁃azepine(BZD)effects that are insensitive to the classical BZD binding site antagonist,flumazenil.Whether the flumazenil-insensitive BZD effects have selectivity on different GABAA recepto...
This work was supported by the National Natural Science Foundation of China(No.21977074);the Science and Technology Projects from the Educational Department of Liaoning Province,China(No.2019LQN02).
A series of pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione derivatives was designed and synthesized,and their neuroprotective activity against SH-SY5Y cell injury induced by N-methyl-D-aspartic acid(NMDA)was evaluated.A...
The benzodiazepines were introduced into medical practice during the 1960s. At the time, they represented a safer alternative to extant therapies used...
The study was financially supported by the Swedish National Board of Forensic Medicine.
There are case reports of offenders inflicting excessive injuries on their victims when under the influence of benzodiazepines.However,the potential association between benzodiazepine influence on the offender and vic...