皮损内注射治疗瘢痕疙瘩的研究进展  

Progress of Intralesional Injections in the Treatment of Keloid

作　　者：李美玲[1] 朱莲花[1] 方宇辉[1] 金哲虎[1] 

机构地区：[1]延边大学附属医院皮肤科,吉林延吉133000

出　　处：《中国皮肤性病学杂志》2017年第10期1139-1140,1144,共3页The Chinese Journal of Dermatovenereology

基　　金：国家自然科学基金项目(81060233);吉林省教育厅"十二五"科学技术研究项目[吉教科合字(2012)第2号];吉林省产业技术研究与开发项目(2013C034);吉林省卫生厅项目(2014Z094)

摘　　要：瘢痕疙瘩是一种以皮肤结缔组织增生和侵袭性生长为主要特征的病理性瘢痕。多在外伤、炎症、手术后形成,好发于胸前、肩胛部、耳垂等部位。暴露部位瘢痕疙瘩影响美观,功能区皮损影响局部活动,且瘢痕疙瘩常伴瘙痒、疼痛、局部过度敏感等,对患者造成沉重心理负担,严重者生活质量受到影响。虽然瘢痕疙瘩在临床上治疗方法多样,但因其形成机制尚不明确,复发率高,故是外科治疗的难题。皮损内注射治疗已广泛应用于国内外瘢痕疙瘩的治疗,本文对其作以综述。Keloid is pathological scar,whose connective tissue hyperplasia and invasive growth as the main characteristics.It is caused by trauma,inflammation,operation wound and often occurs in the chest,scapular,and earlobe.The main symptom is pain,pruritus and over-sensitivity.Exposure site may affect the appearance,the keloid of functional area cause limitation of activity,which brings great psychological burden on the patients,and consequently affect the quality of their lives.Although there are many various therapies,the recurrence is high.The mechanisms of formation are not really clear,so the treatment of keloid becomes a major problem in surgical department.Intralesional injections in the treatment of keloids has been widely used in domestic and international clinic.Here is to make a review of the progress of intralesional injections in the treatment of keloids.

关 键 词：瘢痕疙瘩 皮损内注射 治疗 

分 类 号：R739.5[医药卫生—肿瘤]