NAG-1基因的抗肿瘤效应研究进展  

The Progress and Research on Antitumor Effect of NAG-1 Gene

作　　者：康玥 张小博 郭青龙 KANG Yue ZHANG Xiao-bo GUO Qing-long(China Pharmaceutical University,（College of basic medicine and clinical pharmacy,jiangsu Nanjing 210000)

机构地区：[1]中国药科大学基础医学与临床药学学院,江苏南京210000

出　　处：《世界最新医学信息文摘》2017年第26期59-61,共3页World Latest Medicine Information Electronic Version

摘　　要：NAG-1,作为一种转化生长因子(TGF-β)超家族成员,参与了肿瘤的发生及发展,在众多肿瘤中,都可以检测到NAG-1基因表达的变化。虽然有报道称NAG-1是抗肿瘤形成的组成部分,参与了肿瘤凋亡的过程,但其中包含的机制是非常复杂的,并因肿瘤的微环境不同而改变。其在临床诊断上也起到重要作用。NAG, I,a member of the transforming growth factor （TGF-β）superfamily, was invotved in the occurrence and development of tumors, and the changes Of NAG：I gene expression was detected in numbers of tumors.Although there were reported that NAG- 1 is part of tumor formation and participate in the process of apoptosis, the meChaniSm was very complex and it change for different tumor microenvironments, it also plays an important role on Clinical diagnosis.

关 键 词：NAG-1 肿瘤 诊断 

分 类 号：R73[医药卫生—肿瘤]