CT引导下射频热凝治疗原发性三叉神经痛的临床疗效  

Clinical efficacy of CT-guided radiofrequency thermal coagulation for the treatment of primary trigeminal neuralgia

作　　者：陈华伦[1] 王伍超[1] 郭晓丽[1] 高巍巍[1] 

机构地区：[1]第三军医大学大坪医院(野战外科研究所)疼痛医学科,重庆400042

出　　处：《介入放射学杂志》2017年第10期918-921,共4页Journal of Interventional Radiology

摘　　要：目的探讨运用CT引导下射频热凝治疗原发性三叉神经痛的临床效果。方法选取原发性三叉神经痛患者165例作为研究对象,所有患者采用随机抽签法分成射频热凝组和药物毁损组,射频热凝组患者83例,药物毁损组患者82例。射频热凝组采用CT引导下射频热凝治疗三叉神经痛,药物毁损组采用CT引导下经皮穿刺卵圆孔表阿霉素化学毁损治疗三叉神经痛,于治疗后3个月、6个月、1年、3年进行随访,观察两组患者的VAS评分变化、治疗总有效率及并发症发生率指标。结果射频热凝组优良率明显优于药物毁损组,两组差异有统计学意义(P<0.05);两组并发症发生率比较,射频热凝组明显更低,差异有统计学意义(P<0.05);两组随访期VAS疼痛评分比较,观察组更低,且远期疼痛情况稳定,总体治疗效果突出。结论采用CT引导下射频热凝治疗原发性三叉神经痛的临床效果显著,值得推广应用。Objective To evaluate the clinical effect of CT-guided radiofrequeney thermal coagulation in treating primary trigeminal neuralgia. Methods A total of 165 patients with primary trigeminal neuralgia were selected as research objects. The patients were randomly divided into radiofrequency thermal coagulation group （study group, n=83） and drug damage group （control group, n=82）. For the treatment of trigeminal neuralgia, CT-guided radiofrequency thermal coagulation was carried out in the patients of the study group, and CT-guided percutaneous puncturing of oval foramen with epirubicin injection as chemical damage therapy was employed in the patients of the control group. Follow-up cheek-up was conducted at 3, 6, 12 and 36 months after the treatment. Visual analog score （VAS）, total effective rate and incidence of complications were calculated and the results were compared between the two groups. Results The excellent therapeutic rate of the study group was significantly better than that of the control group, the difference between the two groups was statistically significant （P〈0.05）. The incidence of complications in the study group was remarkably lower than that in the control group, the difference between the two groups was statistically significant （P〈0.05）. The VAS pain score of the study group was much lower than that of the control group. The total therapeutic effect in the study group was more prominent. Conclusion In treating primary trigeminal neuralgia, CT-guided radiofrequency thermal coagulation has excellent clinical effect. Therefore, this technique is worthy of popularization and application in clinical practice.

关 键 词：三叉神经痛 射频热凝 CT引导 

分 类 号：R745.11[医药卫生—神经病学与精神病学]