成人朗格汉斯组织细胞增生症的影像学表现  

Imaging Features of Langerhans Cell Histiocytosis in Adults

作　　者：房国成[1] 王金成[1] 

机构地区：[1]江苏省泰兴市人民医院放射科,江苏泰兴225400

出　　处：《中国CT和MRI杂志》2017年第11期138-140,共3页Chinese Journal of CT and MRI

摘　　要：目的分析成人朗格汉斯组织细胞增生症累及不同系统的的影像表现,提高对该病的诊断水平。方法回顾性分析经手术病理证实5例朗格汉斯组织细胞增生症的影像学表现及临床资料。结果 5例中2例单发,3例多发。累及骨质的病灶多表现为穿凿样、溶骨性及膨胀性骨质破坏,边缘清晰或模糊,部分伴有硬化边,部分可见骨膜反应,MRI上表现为T1WI等信号,T2WI稍高、高信号。发生于中枢神经系统的变病1例现为三脑室漏斗部结节,边缘清晰,MRI增强呈明显强化,另一例表现为神经垂体T1WI信号减低。发生于软组织的表现为软组织增厚,部分形成软组织肿块。结论成人朗格汉斯组织细胞增生症是一种较罕见的疾病,可累及全身各系统,可单发也可多发,病变表现各异,无特异性的影像学表现,因此影像表现结合临床、病理才能确诊。Objective To improve the awareness of the imaging features of Langerhans cell histiocytosis（LCH） in different systems.Methods 5 patients of Langerhans cell histiocytosis comfimled by surgey and histopathology were collected. All imagings were retrospectively analyzed. Results Of these 5 cases, 2 were solitary lesion, and 3 cases were multiple lesions. Involvement of bone lesions show the punched out, soluble osseous bone destruction, and swelling bone destruction, with clear or fuzzy edge, some lesions accompanied by harden edge, and some lesions accompanied with periosteal reaction.l Lesion occurred in the central nervous system which located at the third ventricle infundibulum, and manifested as a nodule which had a clear edge, and showed significantly enhancement on MRI .The lesion manifested as thickening of the soft tissue when occurred in soft tissue.Conclusion Langerhans cells histocytosis is a relatively rare disease and may involves the whole body, the lesion can be single or multiple, with no specific imaging findings. Therefore, the diagnosis of Langerhan＇s cell histiocytosis （LCH） is often difficult and delayed.

关 键 词：朗格汉斯组织细胞增生症 计算机体层成像 磁共振成像 

分 类 号：R733[医药卫生—肿瘤] R445.2[医药卫生—临床医学]