早期胃癌内镜黏膜下剥离术后溃疡愈合的影响因素分析  

Analysis of influencing factors of ulcer healing after endoscopic submucosal dissection in early gastric cancer

作　　者：黄建敏[1] 何利平[1] HUANG Jian-min HE Li-ping(Digestive endoscopy center of Fujian Provincial Hospital South Branch, Fuzhou 350001, China)

机构地区：[1]福建省立医院南院消化内镜中心,福州市350001

出　　处：《临床合理用药杂志》2017年第29期11-12,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的分析内镜黏膜下层剥离术(ESD)术后胃溃疡愈合的影响因素。方法收集医院行ESD治疗患者共112例的临床资料,利用logistic回归分析对年龄、性别、是否患有糖尿病、病灶大小、术后溃疡大小、是否有幽门螺杆菌感染及病灶部位进行分析,研究上述因素对ESD术后胃溃疡愈合的影响。结果糖尿病患者溃疡愈合效果较无糖尿病患者明显不佳,位于贲门、胃窦小弯及胃角的病灶溃疡愈合效果较其他部位病灶好。结论糖尿病病史及病灶位置不同对溃疡的愈合产生影响。Objective To analyze the influencing factors of gastric ulcer healing after endoscopic submucosal dissec- tion （ESD）. Methods The clinical data of 112 patients with ESD treatment were collected. Logistic regression analysis was used to analyze whether age, sex, diabetes mellitus ,lesion size, postoperative ulcer size, Helicobacter pylori infection and lesion location to study the effect of the those factors on the healing of gastric ulcer after ESD. Results The ulcer healing effect of di- abetic patients was significantly worse than that of patients without diabetes mellitus, and the healing effect of ulcer healing in gastric cardia and small curvature of gastric antrum was better than that of other parts. Conclusion The history of diabetes mellitus and the location of diabetes mellitus have different effects on the healing of ulcer.

关 键 词：内镜黏膜下层剥离术(ESD) 溃疡 糖尿病 病灶位置 

分 类 号：R735.2[医药卫生—肿瘤]