新型医用钛合金材料的研发和应用现状  

Development and Application of Novel Biomedical Titanium Alloy Materials

作　　者：于振涛[1,2] 余森[1,2] 程军[1,2] 麻西群[1,2] 

机构地区：[1]西北有色金属研究院,西安710016 [2]西北有色金属研究院陕西省医用金属材料重点实验室,西安710016

出　　处：《金属学报》2017年第10期1238-1264,共27页Acta Metallurgica Sinica

基　　金：国家自然科学基金项目No.31400821;国家重点研发计划项目No.2016YFC1102003;陕西省重点科技创新团队项目No.2016KCT-30;陕西省科技成果转化专项项目No.2016KTCG01-04~~

摘　　要：医用钛合金材料已成为骨科、齿科和心血管等植介入物或器械用主要原材料,但要满足患者临床治疗的长效安全性和功能性,医用钛合金材料的生物及力学相容性仍有待提高。无论是开发新型高强度、低模量等综合性能优良的新型医用钛合金材料,还是立足对传统医用钛合金材料性能的优化升级,确保医用钛合金材料的均质化、高性能、多功能和低成本是扩大其临床应用的基础和关键。本文从医用钛合金材料合金设计、物理冶金、材料加工、组织与性能、表面改性、先进制造及临床应用等诸方面进行综述,并介绍了作者研发团队的最新进展,展望了未来发展趋势及待解决的问题。Biomedical titanium alloy materials have become the main raw materials for orthopedic,dental and cardiovascular implants or devices, but their biological and mechanical compatibility remains to be improved to meet the long-term safety and function in services for clinical application. Whether developing the novel medical titanium alloys with high-strength, low-modulus and other finer comprehensive performance, or upgrading and optimizing the traditional medical titanium alloys, it is the foundation and key to ensuring the structure homogeneity, high performance, versatility and low cost of biomedical titanium alloy materials and expanding its clinical application. The design, physical metallurgy, materials process, microstructure and properties, surface modification, advanced manufacturing and the clinical application of biomedical titanium alloys were introduced, and their latest research progress was reviewed in this paper, together with the recent advances in the author＇s R D team. Finally, the further research and development trend of biomedical titanium alloys are summarized.

关 键 词：医用钛合金 外科植入物 生物及力学相容性 合金设计 物理冶金 超细晶材料 多孔材料 表面改性 

分 类 号：TG146.2[一般工业技术—材料科学与工程] R318.08[金属学及工艺—金属材料]