乳腺癌化疗后轻度认知功能障碍的行为干预  

Intervention on mild cognitive inpairment after chemotherapy for breast cancer patients

作　　者：柴丽君[1] 祁川川 何真[2] 陈建中[1] 

机构地区：[1]郑州大学第二附属医院,河南郑州450014 [2]郑州大学生命科学院,河南郑州450000

出　　处：《中国实用神经疾病杂志》2017年第17期94-95,101,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨认知行为干预对乳腺癌化疗患者认知功能的影响。方法选取2015-01—2015-12我科收治的乳腺癌术后化疗患者60例为研究对象,随机分为干预组30例和对照组30例。对照组行常规治疗,干预组在常规治疗的基础上给予认知行为干预。应用蒙特利尔评估量表(MoCA)分别测试2组化疗前后的认知功能情况。结果 2组年龄、文化程度、病理分期及化疗前认知功能比较,差异无统计学意义(P>0.05)。干预组化疗后MoCA评分高于对照组,记忆能力、注意力、执行能力比较差异有统计学意义(P<0.05)。结论认知行为干预能显著提高乳腺癌术后化疗患者的认知功能。Objective To observe the effects of the cognitive behavioral therapy on postoperative cognitive ability of breast cancer patients with adjuvant chemotherapy.Methods 60 breast cancer patients with adjuvant chemotherapy in our department from January to December 2015 were randomly selected as research objects.They were divided into the control group(30cases)and the experimental group(30cases).Both groups received conventional treatment,while the experimental group received extra training of the cognitive behavioral therapy.MoCA was adopted to respectively test the cognitive ability of these two groups of patients before and after chemotherapy.Results The differences between the control group and the experimental group in terms of age,educational level,pathological stages,the cognitive ability before chemotherapy and other indicators were not statistically significant(P>0.05).The MoCA score of patients in the experimental group was higher than that of the control group with comparative differences in terms of number,memory ability,attention ability and executive capacitive were all statistically significant(P<0.05).Conclusion The cognitive behavioral therapy can effectively improve the postoperative cognitive ability of breast cancer patients with adjuvant chemotherapy.

关 键 词：乳腺癌 化疗 轻度认知功能障碍 认知行为干预 神经心理学测验 

分 类 号：R749.29[医药卫生—神经病学与精神病学]