睡眠-觉醒形成对长期昏迷预后评估的临床研究  

Clinical study of the formation of sleep-awakening to prognostic assessment of persistent vegetable state patients

作　　者：申天喜[1,2,3] 郭成军 胡刚 方有传 胡愿 郭彪 林丙来 

机构地区：[1]马鞍山市中心医院,安徽马鞍山243000 [2]安徽省皖南康复医院芜湖市第五人民医院神经外科,安徽芜湖241000 [3]武警8690部队医院,江苏宜兴214200

出　　处：《中国实用神经疾病杂志》2017年第18期30-31,共2页Chinese Journal of Practical Nervous Diseases

基　　金：芜湖市科技计划项目(编号2014hm22)

摘　　要：目的探讨睡眠-觉醒形成对长期昏迷患者病情及预后的评估价值。方法回顾1984-08-2016-08住院患者,分析长期昏迷患者睡眠-觉醒形成的时间、周期规律与存活、好转、预后的关系。结果对119例患者对照分析发现,睡眠-觉醒形成的时间越早,生存率越高,约占87.4%。周期规律越接近正常人24h生物钟,存活率越高,约81.5%,病情越稳定。患者进入长期昏迷病程,40~50d形成睡眠-觉醒周期,各组间PVS脑复苏评分差异有统计学意义(P<0.05)。结论 PVS患者形成睡眠-觉醒周期时间越早,存活率越高,病情越稳定,脑复苏评分越高。Objective To explore the value of sleep-awakening circadian to assess the condition and prognosis of persistent vegetable state patients.Methods Clinical data of the patients from August 1984 to August 2016 were reviewed,and the relationships among the time,regulation of formation of sleep-awakening of wakefulness and the state of survival,improvement and prognosis of patients in persistent vegetable state were analyzed.Results The earlier the sleep-awakening formation,the higher the survival rate,which is about 87.4%.The more normal the circadian rhythm is,the more likely it is to have a 24 hour clock,the higher the survival rate,which is about 81.5%,and the more stable condition.The patient entered a long coma course,and formed a sleep wake cycle after 40~50days,there were statistically significant differences on the PVS scores among the groups(P<0.05).Conclusion The patients who have earlier sleep-awakening circadian have higher survival rate,and more stable condition and higher PVS scores.

关 键 词：长期昏迷 睡眠-觉醒 生存率 

分 类 号：R741.041[医药卫生—神经病学与精神病学]