伴焦虑牙周炎患者基础治疗效果的探究  

The effcet of anxiety on chronic periodontitis before and after periodontal initial therapy

作　　者：周冰[1] 薛毅[2] 吴仲寅[2] 张永红[2] 

机构地区：[1]河北医科大学,河北石家庄050000 [2]石家庄白求恩国际和平医院口腔科,河北石家庄050000

出　　处：《全科口腔医学电子杂志》2017年第8期1-3,共3页Electronic Journal of General Stomatology

摘　　要：目的探究焦虑对牙周基础治疗前后龈沟液弹性蛋白酶水平的影响。方法选取的中重度牙周炎患者27例,根据焦虑自评量表(SAS)分为焦虑组13例、对照组14例。检查并记录牙周基础治疗前及治疗后3个月的临床指标,采用底物法检测龈沟液内弹性蛋白酶(EA)水平。结果牙周基础治疗后,两组患者牙周临床指标及龈沟液内弹性蛋白酶水平与治疗前相比明显降低(P<0.05);基础治疗前,焦虑组GCF-EA水平高于对照组(P<0.05);牙周基础治疗后焦虑组PD、CAL、GCF-EA改善程度不及对照组(P<0.05)。结论焦虑是影响牙周基础治疗的不利因素,GCF-EA可能是焦虑影响牙周组织修复机制之一。Objective To analyze the effect of anxiety on the basic therapy of patients with periodontitis,so as to provide a theoretical basis for the adjuvant treatment of periodontitis.Methods 27 patients were evaluated by self-rating anxiety scale（SAS）a total of 13 cases that with SAS≥50 were selected as anxiety periodontitis（AP）;a total of 14 cases that with SAS〈50 were selected as Non-anxiety Periodontitis group（NP）.Clinical indexes and GCF-EA of test teeth were recorded before and after treatment.The EA level were detected by substrat （Meosuc-ala-ala-pro-val-NA） method,and the data was statistically analyzed by SPSS21.0 software.Results PD,CAL in two groups were decreased after initial treatment （P〈0.05）.Compared with the anxiety group,PD,CAL and the level of EA were signifcantly decreased（P〈0.05）.Conclusion Anxiety may be unfavorable factors of the initial periodontal therapy in periodontitis,GCF-EA may be an auxiliary indicator to evaluate the prognosis of chronic periodontitis.

关 键 词：焦虑 牙周基础治疗 慢性牙周炎 弹性蛋白酶 

分 类 号：R781.4[医药卫生—口腔医学]