骨髓间充质干细胞与角膜损伤修复的研究现状  

Progress on bone marrow mesenchymal stem cells for corneal wound healing

作　　者：赵云[1] 于莎莎 ZHAO Yun YU Sha-Sha

机构地区：[1]天津市眼科医院天津市眼科学与视觉科学重点实验室天津市眼科研究所天津医科大学眼科临床学院,天津市300020

出　　处：《眼科新进展》2017年第11期1093-1096,共4页Recent Advances in Ophthalmology

摘　　要：骨髓间充质干细胞是一种主要存在于骨髓中具有自我更新和多向分化潜能的干细胞。目前大量国内外研究证实,骨髓间充质干细胞可以分化为角膜上皮细胞、角膜内皮细胞、角膜缘干细胞,并对眼表损害的修复有重要作用。本文旨在总结骨髓间充质干细胞在角膜损伤修复的基础研究和临床治疗等方面的研究进展。Bone marrow stem cells （BMSCs） are a type of self-renewing,multipotential stem cell groups that mainly located in bone marrow.At present,many research groups,domestic and abroad,have reported that BMSCs can not only differentiate into corneal epithelial cells,corneal endothelial and corneal limbus stem cells,but also play an important role in ocular surface repair.The aim of this article is to summarize the progress on BMSCs in basic and clinical corneal researches.

关 键 词：骨髓间充质干细胞 角膜 分化 

分 类 号：R772.2[医药卫生—眼科]