颈动脉支架植入术治疗颈内动脉次全闭塞的临床研究  

Clinical study of carotid artery stenting on treating near occlusion of internal carotid artery

作　　者：季蕾[1] 蒋颖[1] 岳春贤 刘猛[1] 李达文 吴坚[1] 练学淦[1] JI Lei JIANG Ying YUE Chun-xian et al(Department of Neurology, the Third Affiliated Hospital, Soochow University, Changzhou 213003, China)

机构地区：[1]苏州大学附属第三医院神经内科,常州213003

出　　处：《临床神经病学杂志》2017年第5期355-357,共3页Journal of Clinical Neurology

基　　金：江苏省社会发展项目(BE2016659);常州市社会发展项目(CE20165026)

摘　　要：目的探讨颈动脉支架植入术(CAS)治疗颈内动脉次全闭塞(ICA-NO)的临床效果。方法纳入2011年~2016年本中心完成的颈内动脉支架植入患者133例,其中ICA-NO患者31例(NO组),非ICANO患者102例(对照组)。比较两组临床资料及手术成功率、术中及术后并发症的发生率。结果 NO组临床表现为TIA、脑梗死的患者比例明显高于对照组(P=0.027)。所有患者均成功进行了CAS治疗。NO组发生低血流动力学状态、重度血管痉挛的比例(87.10%,70.97%)均明显高于对照组(35.29%,16.67%)(均P<0.05)。两组术后90 d内缺血性脑血管事件发生率的差异无统计学意义(P=0.664)。结论 CAS治疗ICA-NO是安全有效的。Objective To explore the clinical effects of carotid artery stenting（ CAS） on treating near occlusion of internal carotid artery（ ICA-NO）. Methods A total of 133 patients underwent CAS procedure during 2011-2016 were included in this study. And there were 31 patients with ICA-NO（ NO group） and 102 patients without ICA-NO（ control group）. The clinical data,the success rate of CAS and the incidence of complications before and after CAS were compared between the two groups. Results The rate of patients performed as TIA or cerebral infarction of NO group was significantly higher than that in control group（ P = 0. 027）. Successful CAS insertion was achieved in all patients. The incidence of low hemodynamic state and severe vasospasm in NO group（ 87. 10%,70. 97%） were both significantly higher than those in control group（ 35. 29%,16. 67%）（ all P〈0. 05）. There was no statistical significant difference of the incidence of ischemic events at 90 d after CAS between the two groups（ P = 0. 664）.Conclusion CAS is safe and effective for treating ICA-NO.

关 键 词：颈内动脉 次全闭塞 支架植入术 临床结果 

分 类 号：R743.3[医药卫生—神经病学与精神病学]