中老年人群腰臀比对颈动脉斑块检出率的影响  

Effects of waist-to-hip ratio on the detection rate of carotid artery plaque in the middle-aged and the elderly

作　　者：张丽[1] 吴成忠[1] 高永生[3] 陈磊[1] 刘丽英[2] 王月辉[4] 黄玮[1] 孙俊新[2] 张宝霞 刘秀荣[2] Zhang Li Wu Chengzhong Gao Yongsheng Chen Lei Liu Liying Wang Yuehui Huang Wei Sun Junxin Zhang Baoxia Liu Xiurong(Ultrasound Examination Department, Kailuan General Hospital, Tangshan 063000 chin)

机构地区：[1]开滦总医院彩超室,河北省唐山市063000 [2]开滦总医院查体中心,河北省唐山市063000 [3]开滦总医院泌尿外科,河北省唐山市063000 [4]开滦精神卫生中心睡眠病区 [5]开滦林南仓医院内科

出　　处：《中国综合临床》2017年第8期677-680,共4页Clinical Medicine of China

基　　金：河北省科技计划项目（62777182）

摘　　要：目的 探讨中老年人群腰臀比（WHR）对颈动脉斑块形成的影响.方法 选取2010年6月至2011年10月符合入选标准的5 099名参加开滦集团有限责任公司健康体检员工（年龄≥40岁、既往无缺血性脑卒中、短暂性脑缺血发作、心肌梗死者）进行统一问卷调查,并行血液生化及颈动脉超声检查.依据WHR按4分位法将观察对象分为4组,比较4组间颈动脉斑块的检出率.对颈动脉斑块的相关危险因素进行多因素Logistic回归分析.结果 （1）颈动脉斑块的检出率随着WHR的增加而逐渐升高,第一、二、三、四分位组的检出率分别为20.7%（571/2 753）21.9%（604/2 753）、27.5%（758/2 753）和29.8%（820/2 753）,组间比较差异有统计学意义（P=0.000）.（2）应用Logistic回归模型分析影响颈动脉斑块检出率的多因素分析,校正其他因素后,与第一分位组比较,第二、三、四分位组颈动脉斑块检出率均有增加,OR值分别为1.23（95%CI：1.10~1.54）、1.65（95%CI为1.52~2.13）、1.67（95%CI为1.54~2.17）.结论 中老年人群WHR增大可能增加颈动脉斑块形成的风险.Objective To investigate the effects of waist-to-hip ratio （WHR） on the formation of carotid plaque in the middle-aged and elderly people.Methods A total of five thousand and ninety-nine participants who have taken physical examination in Tangshan Kailuan Company from June 2010 to October 2011（above 40 years old,no previous history of ischemic stroke,transient ischemic attack,myocardial infarction） were enrolled in this study.Questionnaire survey,blood biochemical and carotid artery ultrasound examination were used to examine the subjects.According to WHR,quartile division was used to divide the subjects into four groups.The detection rates of carotid plaque among the 4 groups were compared.Multivariate logistic regression analysis was used to analyze the factors effecting carotid artery plaques.Results （1） The detection rate of carotid artery plaque increased with the increase of WHR,the rates of the first,second,third and fourth group were 20.7% （571/2 753）,21.9% （604/2 753）,27.5% （758/2 753） and 29.8% （820/2 753） respectively.The difference was statistically significant（P=0.000）.（2） Logistic regression model was used to analyze multiple factors affecting the detection rate of carotid plaque.After the correction of other factors,compared with the first group,the carotid artery plaque detection rate in the second,third,fourth group were all increased,the OR values were 1.23（95%CI：1.10~1.54）,1.65（95%CI：1.52~2.13）,1.67（95%CI：1.54~2.17）,respectively.Conclusion The increased WHR in the middle-aged and elderly population may increase the risk of carotid plaque formation.

关 键 词：腰臀比 颈动脉斑块 流行病学研究 

分 类 号：R743[医药卫生—神经病学与精神病学]