保乳手术与改良根治术治疗86例早期乳腺癌患者疗效分析  

Analysis of Clinical Effect of Breast-conserving Surgery and Modified Radical Mastectomy on 86 Cases of Early Breast Cancer

作　　者：陈惠忠[1] 

机构地区：[1]惠安县医院普外科,福建惠安362100

出　　处：《中外医疗》2017年第26期62-64,共3页China & Foreign Medical Treatment

摘　　要：目的探讨保乳手术和改良根治术治疗早期乳腺early-stage breast cancer,EBC)的临床疗效。方法方便选取该院自2013年6月—2015年6月间收治的TNM分期为Ⅰ期的EBC患者86例作为研究对象,依据手术指征和患者意愿分成两组,行保乳手术治疗的患者46例,采用改良根治术患者40例,对比两组患者术后并发症发生率、使用乳腺癌生活质量量表(QLQ-BR23)评估两组患者手术治疗效果;随访2年,记录两组患者复发/转移率、死亡率情况。结果保乳手术组患者术后并发症发生率为4.35%,改良组为22.50%(χ~2=6.320,P<0.05);术后6个月保乳组患者QLQBR23评分优于改良组,组间数据对比差异有统计学意义(P<0.05);术后随访2年,保乳组患者复发率为4.35%、转移率为2.17%、死亡率为4.35%,改良组依次为0.00%、5.00%、5.00%,组间数据差异无统计学意义(P>0.05)。结论早期乳腺癌患者采用保乳手术治疗并发症发生率低、术后患者的生活质量表现优秀,术后近期复发率和死亡率与改良根治术无显著差异,因此值得推广使用。Object ive This paper tries to inves tigate the cl inical efficacy of breast -conserving surgery and modified radical mastectomy in the treatment of ear ly-stage breast cancer （EBC）. Methods Convenient select ion 86 pat ients with s tage TNM phase I from June 2013 to June 2015 were selected as the subjects. According to the indications of surgery and the inten-tion of pat ients, the pat ients were divided into two groups. 46 pat ients underwent breast conserving surgery, and 40 cases underwent modified radical mastectomy. The incidence of pos toperative complicat ions was compared between the two groups. The efficacy of the two groups was evaluated using the breast cancer quality of life scale （QLQ-BR23）. After the 2 years5 fol low-up, recur rence/metastasis rate, mortality rate of the two groups were recorded. Results The incidence of post-operat ive complicat ions was 4.35% in the breast conserving surgery group and 22.50% in the modified group （x2=6.320,P〈 0.05）. The QLQ-BR23 score in the breast -conserving group was bet ter than that in the improved group af ter six months of surgery （P〈0.05）. After two years’ fol low-up, the recur rence rate was 4.35%, the metas tas is rate was 2.17%, the mortality rate was 4.35%, the improvement group was 0.00%,5.00%, 5.00%. There was no signif icant difference between the two groups（P〉0.05）. Conclusion The incidence of complicat ions in breast cancer pat ients treated with breast conserving surgery was low, and the quality of life of pat ients was excellent. The recur rence rate and mortality rate were not signif icantly differ-ent from those of modified radical mastectomy. Therefore, it is worth appl icat ion and promotion.

关 键 词：乳腺癌 保乳手术 改良根治术 QLQ-BR23量表 

分 类 号：R737[医药卫生—肿瘤]