食物不耐受相关性赋能教育对溃疡性结肠炎患者的效果研究  

Effect Research of Empowerment Education Related with Food Intolerance on Ulcerative Colitis Patients

作　　者：张迎迎[1] 朱丽璎 胡芳[2] 李凯钰 高森阳 刘刚[1] 

机构地区：[1]天津医科大学总医院普外科,天津市300052 [2]天津医科大学总医院护理部,天津市300052

出　　处：《中国全科医学》2017年第14期1671-1674,1679,共5页Chinese General Practice

基　　金：黎介寿院士肠道屏障研究专项基金资助项目(LJS_201008)

摘　　要：目的研究食物不耐受相关性赋能教育对溃疡性结肠炎(UC)患者的干预效果,为临床指导提供依据。方法选取2013年9月—2014年8月在天津医科大学总医院住院的UC患者89例,根据其接受食物不耐受相关性赋能教育的意愿分为试验组(n=47)和对照组(n=42)。试验组患者接受面对面的食物不耐受相关性赋能教育,对照组接受传统电话随访健康教育,1次/2周,持续干预6个月。采用酶联免疫吸附试验(ELISA)检测患者食物不耐受情况;并于干预前及干预6个月后采用简明健康状况调查问卷(SF-36)评估患者生活质量;测量体质指数(BMI)及血清总蛋白(TP)、清蛋白(ALB)、前清蛋白(PA)、转铁蛋白(TRF)水平评估患者营养状况;采用Southerland疾病活动指数(DAI)评分系统评估患者疾病活动程度。结果 89例UC患者食物不耐受阳性率为67.4%(60/89)。试验组患者食物不耐受阴性14例,轻度不耐受6例,中度不耐受1例,重度不耐受26例;对照组患者分别为15、4、1、22例,两组食物不耐受发生情况比较,差异无统计学意义(Z=0.416,P=0.677)。干预前,两组SF-36各维度得分比较,差异均无统计学意义(P>0.05);干预后,试验组躯体职能、总体健康、社会功能、情感职能、心理卫生得分均高于对照组以及同组干预前(P<0.05)。干预前,两组患者BMI、TP、ALB、PA、TRF水平比较,差异均无统计学意义(P>0.05);干预后,试验组ALB水平高于对照组和同组干预前(P<0.05)。干预前,两组Southerland DAI评分比较,差异无统计学意义(t=0.219,P=0.827);干预后,试验组Southerland DAI评分低于对照组(t=2.726,P=0.008)。结论对UC患者进行食物不耐受相关性赋能教育可以提高患者生活质量及营养状况,改善疾病预后。Objective To investigate the intervention effect of empowerment education related with food intolerance onulcerative colitis （ UC） patients , and to provide basis for clinical supervision. Methods 89 UC patients who had beenhospitalized in Tianjin Medical University General Hospital from September 2013 to August 2014 were selected. The patients weredivided into experimental group （ n = 47 ） and control group （ n = 42 ） according to their willingness of accepting empowerment education. Experimental group received face - to - face empowerment education related with food intolerance , and control group received traditional health education of telephone follow - up , 6 - month sustained intervention was made biweekly. Enzyme -linked immunosorbent assay （ELISA） was applied to detect food intolerance conditions of patients; before intervention and sixmonths after intervention , short form health survey （SF-36） was used to access patients＇ quality of life; body mass index（BMI） and levels of serum total protein （TP） , albumin （ALB） , prealbumin （PA） and transferrin （TRF） were to evaluate patients＇ nutritional status; the extent of disease activity of patients was accessed by using Southerland DAI scoring system. Results The positive rate of food intolerance of UC patients was 67. 4% （60/89） . For patients in experimental group ,14 were negative food intolerance, 6 mild intolerance, 1 moderate intolerance and 26 severe intolerance; while for patients in control group, the above four numbers were 15,4 , 1 and 22 respectively, the comparison of occurrence of food intolerance between two groups was not significantly different （Z =0.416,P = 0. 677 ） . Before intervention, there was no significant difference between the two groups in SF-36 scores of every dimension （ P 〉 0. 05 ） ; after intervention, scores of physical function, general health, social function, emotional function, mental health

关 键 词：结肠炎 溃疡性 食物不耐受 赋能教育 疾病活动程度 

分 类 号：R574.62[医药卫生—消化系统]