书虱代谢抗性研究进展  

Advances in Metabolic Resistance to Insecticides in Psocids( Psocoptera: Liposcelididae)

作　　者：景田兴 郎宁 豆威[1] 魏丹丹[1] 王进军[1] 

机构地区：[1]西南大学植物保护学院昆虫学与害虫控制工程重庆市重点实验室,重庆400715

出　　处：《中国粮油学报》2017年第10期191-196,共6页Journal of the Chinese Cereals and Oils Association

基　　金：国家自然科学基金(31301667);重庆市基础与前沿研究计划(cstc2015jcyj A80009)

摘　　要：书虱是一类在全球范围内均有分布的仓储害虫,对原粮特别是种子粮造成极大威胁,可造成严重经济损失。近年来,书虱抗药性问题日益突出,在其抗药性机制方面的研究也越来越深入。在诸多抗性机制中,代谢抗性占据了重要的地位。其中,三大代谢解毒酶细胞色素P450单加氧酶(P450)、酯酶(ESTs)和谷胱甘肽-S-转移酶(GSTs)在书虱代谢抗性中扮演重要角色。本文从生理生化、转录组学与分子生物学等方面,对书虱代谢抗性的研究进行阐述,为书虱的抗性防控提供借鉴。The psocids, of the genus Liposcelis are kinds of worldwide stored - product insects. Outbreaks can lead to significant economic losses, especially to the unprocessed food grains and seeds. Recently, apparent insecticides resistances have been observed in psocids and numerous studies focusing on this resistance problem have been done and a series of papers about the mechanisms of resistance in psocids have been published. Resistant mechanisms mainly involve in metabolic resistance induced by increases in the metabolic capabilities of detoxificative enzymes, and target site resistance by decreases in target site sensitivity. This review mainly focused on mechanisms of metabolic resistance associated with the three major enzymes, Cytochrome P450 monooxygenases （ P450s）, Estrases （ ES- Ts）, and Gluthione -S -transferases （GSTs） in psocids. Based on the researches on biochemical and toxicological characterizations, transcriptomies, and molecular biology of P450s, ESTs and GSTs genes in Liposcelis species, this study could provide a foundation for developing psocids management strategies.

关 键 词：书虱 代谢抗性 转录组 P450 酯酶谷 胱甘肽-S-转移酶 

分 类 号：S379.5[农业科学—农产品加工]