施杞教授治疗椎动脉型颈椎病用药规律的聚类分析  

Cluster Analysis on Medication Rule of Professor Shi Qi for Treating Cervical Spondylosis of Vertebral Artery Type

作　　者：徐保平[1,2] 田子睿 李振军[1,2] 王晓涛[1,2] 潘艳芳[1,2] 崔学军[1,2] 

机构地区：[1]上海中医药大学附属龙华医院,上海200032 [2]上海中医药大学脊柱病研究所,上海200032

出　　处：《世界科学技术-中医药现代化》2017年第8期1324-1329,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：上海市科委中医重点项目(No 14401970400):中医综合治疗脊髓型颈椎病的多中心临床研究;负责人:王拥军;筋骨理论与治法教育部重点实验室(教科<2009>98号):负责人:王拥军;国家科技部重点领域创新团队计划项目(2015RA4002):负责人:王拥军

摘　　要：目的:总结施杞教授治疗椎动脉型颈椎病的临床用药规律并探索其学术思想。方法:收集2009-2015年龙华医院施杞教授门诊就诊且符合纳入标准的椎动脉型颈椎病医案265例,对纳入医案中的药物利用SPSS 21.00软件进行频数分析和聚类分析。结果:总计使用药物202种,最常用的中药是川芎、柴胡、怀牛膝、党参、天麻5味药物。聚类分析发现施杞教授临证常用的药物是活血化瘀药、补虚药、平肝熄风药,祛风湿药,圣愈汤和天麻钩藤饮是施杞教授治疗椎动脉型颈椎病的核心处方。结论:聚类分析结果体现了施老治疗椎动脉型颈椎病气血并重,重在肝肾,兼顾痰瘀,标本同治的学术思想,在一定程度上揭示了施老治疗椎动脉型颈椎病的用药规律,可以指导临床用药。This study was aimed to summarize the clinical medication rule of professor Shi Qi in the treatment of cervical spondylosis of vertebral artery type （CSA）, in order to explore the academic ideas. A total of 265 CSA cases from professor Shi Qi＇ s outpatient clinic were collected in Longhua Hospital from 2009 to 2015. Frequency analysis and cluster analysis were conducted on used herbal medicine from included cases by SPSS 21.00 software. The results showed that there were a total of 202 types of herbs used. The five most commonly used herbs were Rhizoma Ligustici Wallichii, Radix bupleuri, Radix Achyranthis Bidentatae, Codonopsis and Gastrodia elata. The cluster analysis revealed that professor Shi Qi frequently used Huo-Xue Hua-Yu herbs, Bu-Xu herbs, Ping-Gan Xi-Feng herbs, Qu-Feng-Shi herbs. Sheng-Yu decoction and Tian-Ma C, ou-Teng decoction were the core prescriptions used by professor Shi Qi in the treatment of CSA. It was concluded that the cluster analysis showed that academic ideas of professor She in the treatment of CSA was to pay equal attention to both qi and blood, to focus on liver and kidney, as well as to remove phlegm and blood stagnation, to treat both the branch and the root. The cluster analysis revealed a certain medication rule of professor Shi Qi in the treatment of CSA. It can be used as guidance in the clinical practice.

关 键 词：椎动脉型颈椎病 施杞教授 聚类分析 用药规律 

分 类 号：R274.9[医药卫生—中西医结合]