肝郁脾虚证的现代生物学基础探讨  

Discussion on Modern Biological Basis of Liver-qi Stagnation and Spleen Deficiency Syndrome

作　　者：刘燕[1,2] 陈家旭[3,2] 邹小娟[2] 蒋时红[1] 王明晶[1] 张中华[1] 许亚辉 

机构地区：[1]河南中医药大学,郑州450046 [2]湖北中医药大学,武汉437001 [3]北京中医药大学,北京100029

出　　处：《世界科学技术-中医药现代化》2017年第8期1401-1405,共5页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金(No.81473597)个肝郁脾虚型抑郁症海马-杏仁核神经活性甾体变化及逍遥散的作用机理,负责人:陈家旭;北京市自然科学基金(No.7152093)基于中枢星形胶质细胞ATP释放的逍遥散抗抑郁机理研究,负责人:陈家旭请补充两项基金的名称,负责人

摘　　要：肝郁脾虚证可见于多种临床疾病,如慢性肝炎、肝硬化、慢性胃炎、消化性溃疡、肠易激惹综合征、精神病等。疾病特点决定着证候的症状特点及辨证标准,因此,不同疾病的肝郁脾虚证的临床表现和诊断标准也不尽相同。本文从神经系统、内分泌系统、消化系统、循环系统、免疫系统和代谢系统等几个方面对肝郁脾虚证的现代生物学基础进行了总结,以便为肝郁脾虚证的现代生物学基础研究提供参考。Liver-qi stagnation and spleen deficiency syndrome can be seen in a variety of clinical diseases, such as chronic hepatitis, liver cirrhosis, chronic gastritis, peptic ulcer, irritable bowel syndrome （IBS）, psychosis and so on. Disease characteristics determine the symptom characteristic and criterion of syndrome differentiation and treatment. Therefore, different diseases with liver-qi stagnation and spleen deficiency syndrome have different clinical manifestation and diagnostic criteria. This paper summarized the modem biological basis of liver-qi stagnation and spleen deficiency syndrome from the nervous system, endocrine system, digestive system, circulatory system, immune system and metabolic system, in order to provide reference for researches on modern biology basis of liver-qi stagnation and spleen deficiency syndrome.

关 键 词：肝郁脾虚证 证候生物学基础 辨证论治 临床表现 诊断标准 

分 类 号：R229[医药卫生—中医基础理论]