血管内NK/T细胞淋巴瘤的研究进展  

Research progress in intravascular NK/T cell lymphoma

作　　者：徐嘉雯[1] 王宏量 赵文博[3] 曹智新[1] 

机构地区：[1]山东大学附属省立医院病理科,济南250021 [2]山东省职业卫生与职业病防治研究院山东省医学科学院,济南250062 [3]山东大学附属省立医院血液科,济南250021

出　　处：《临床与病理杂志》2017年第9期1932-1935,共4页Journal of Clinical and Pathological Research

基　　金：国家自然科学基金(81202092);山东省重点研发计划项目(2015GSF118015;2016GSF201087)~~

摘　　要：血管内NK/T细胞淋巴瘤(intravascular NK/T cell lymphoma,IVNKTL)罕见,其特征性表现为肿瘤性淋巴细胞选择性生长于血管腔内。不同地域患者临床表现多样且缺乏特异性,因此临床诊断困难。IVNKTL具有病程进展快、伴EBV感染、好发于亚洲,且以中国人多发等特点。在肿瘤未累及到多器官前进行早期诊治可有效改善IVNKTL患者的预后。Intravascular NK/T cell lymphoma（IVNKTL） is a rare type of malignant lymphoma characterized by the selective growth of neoplastic lymphocytes within the lumina of blood vessels. The clinical manifestations are diverse and non-specific in different geographical areas, making diagnosis difficult. IVNKTL is a highly aggressive and EBVassociated lymphoma that is prone to develop in Asian patients, particularly in Chinese patients. Early diagnosis and treatment before multi-organ involvement could effectively improve the prognosis of IVNKTL patients.

关 键 词：血管内淋巴瘤 NK/T细胞淋巴瘤 临床病理学 鉴别诊断 

分 类 号：R733[医药卫生—肿瘤]