NAFLD相关肝细胞癌的发病机制  

Pathogenesis of NAFLD associated hepatocellular carcinoma

作　　者：冯胜虎[1] 成军[2,3] FENG Sheng-hu CHENG Jun(Peking University Ditan Teaching Hospital, Beijing 100015, China Institute of lnfectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China Beijing Key Laboratory of Emerging Infectious Diseases, Beijing 100015, China)

机构地区：[1]北京大学北京地坛医院教学医院,北京100015 [2]首都医科大学附属北京地坛医院传染病研究所,北京100015 [3]新发突发传染病研究北京市重点实验室,北京100015

出　　处：《中国肝脏病杂志（电子版）》2017年第3期8-12,共5页Chinese Journal of Liver Diseases：Electronic Version

基　　金：北京市医管局扬帆计划和登峰计划(ZYLX201402;DFL20151701);北京市自然科学基金重点项目(7161006)

摘　　要：越来越多的研究证实,非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)是肝细胞癌(hepatocellular carcinoma,HCC)的独立危险因素,揭示NAFLD发生机制及其向HCC转变的可能机制对于NAFLD及HCC的预防和治疗具有重要意义。本文对NAFLD相关HCC发病机制的相关研究进行综述,便于进一步探索。More and more studies have proved that non-alcoholic fatty liver disease（NAFLD） is an independent risk factor for hepatocellular carcinoma（HCC）. In view of this, it is important to reveal the mechanism of NAFLD and the possible mechanism of transformation from NAFLD to HCC. In this paper, the related research on the pathogenesis of NAFLD related HCC is summarized, which is convenient for further exploration.

关 键 词：脂肪肝 非酒精性 肝细胞癌 

分 类 号：R735.7[医药卫生—肿瘤]