短波紫外线治疗仪治疗急性白血病患者化疗后口腔黏膜炎疗效评价  

Curative Effect Evaluation of Short-wave Ultraviolet Ray Therapy Apparatus for Oral Mucositis of Acute Leukemia Patients

作　　者：李芳[1] 秦月兰[1] 彭贤玉[1] 杨慧奇 周明[1] 

机构地区：[1]湖南省人民医院血液科,湖南长沙410005

出　　处：《医学临床研究》2017年第10期1898-1899,1903,共3页Journal of Clinical Research

基　　金：湖南省卫生计生委2015年度科研计划课题项目（B2015-90）

摘　　要：【目的】探讨短波紫外线治疗仪治疗急性白血病住院患者化疗后口腔黏膜炎（OM）的临床疗效。【方法】按照入院先后顺序不同将接受化疗后出现OM的急性白血病住院患者分为观察组和对照组,对照组采用亚叶酸钙、维生素B12漱口液漱口、表面喷涂金因肽、金喉健等治疗;观察组在对照组的基础上加用ZYY-9增强型短波紫外线治疗仪进行照射治疗。观察两组在治疗14 d后OM的治疗效果。【结果】治疗14 d后,观察组痊愈率（89.3%）明显高于对照组痊愈率（64.3%）;观察组在疼痛感消失时间、溃疡面积缩小50%和溃疡面愈合所需时间上明显短于对照组,差异均有统计学意义（均P〈0.05）。【结论】短波紫外线治疗仪可提高OM的痊愈率,缩短OM的痊愈时间,使用安全、方便,患者易于接受,值得临床推广应用。【Objective】To explore the curative effect evaluation of short-wave ultraviolet ray therapy for oral mucositis（OM） with acute leukemia patients.【Methods】Acute leukemia patients with oral mucositis were divided into the observation group and the control group according to the order of admission. Patients in the control group were treated by conventional methods, while patients in the observation group received irradiation treatment by ZYY - 9 enhanced short-wave ultraviolet ray therapy apparatus in addition to conventional treatment. The therapeutic effect for OM in the two groups was observed within 14 days.【Results】The recovery rate of the observation group was 89.3% which was obviously higher than that of the control group （64.3%） within 14 days, and the difference was statistically significant （P〈0.001）. In the observation group, the average time required for the disappearance of pain, the 50% reduction in ulcer area of OM and oral mucositis healing time were significantly shorter than those in the control group with statistically significant difference （P〈0.001）.【Conclusion】Short-wave ultraviolet irradiation treatment can obviously improve the recovery rate of OM and shorten its healing time. The instrument is convenient and safe to use with broad clinical popularization and application.

关 键 词：紫外线疗法 白血病/药物疗法 急性病 口炎 口疮性/放射疗法 

分 类 号：R733.7[医药卫生—肿瘤]