类赖氨酰氧化酶1在翼状胬肉中的表达  

Expression of lysyloxidase like 1 in pterygium

作　　者：覃瑞[1] 马文豪[1] 罗燕妮[1] 施智敏[1] 陆丽丽 覃志良 

机构地区：[1]右江民族医学院附属医院眼科,广西百色533000

出　　处：《中国现代医学杂志》2017年第25期28-31,共4页China Journal of Modern Medicine

基　　金：百色市科学研究与技术开发项目(No:百科技20160619);广西壮族自治区中青年教师基础能力提升项目[No:桂教科研(2017)16号]

摘　　要：目的通过检测正常结膜组织和翼状胬肉中类赖氨酸氧化酶1(LOXL-1)的表达,探讨LOXL-1在翼状胬肉发展过程中的影响及意义。方法采用免疫组织化学检查正常结膜组织(19例)和翼状胬肉组织(25例)中LOXL-1的表达情况,测定两组免疫组织化学结果的光密度值。结果正常结膜组织与翼状胬肉中LO XL-1的光密度值比较,差异有统计学意义(P<0.05),正常结膜组织偏低。结论翼状胬肉组织中LO XL-1的表达较正常结膜组织高,LOXL-1在翼状胬肉发展中起到了促进的作用。Objective To compare the expression of lysyloxidase like 1(LOXL-1) in normal conjunctiva tissues and pterygium, and explore the influence and significance of LOXL-1 in the course of pterygium development.Methods Using immunohistochemistry, LOXL-1 expression in normal conjunctiva tissues(19 cases) and pterygium(25 cases) was examined, optical density value was detected. Then t test was carried out. Results The optical density value in the normal conjunctiva tissues was lower than that in the pterygium(P < 0.05). Conclusions The expression of LOXL-1 in pterygium is higher than that in normal conjunctiva tissues. LOXL-1 plays an important role in promoting the development of pterygium.

关 键 词：类赖氨酸氧化酶1 翼状胬肉 表达 

分 类 号：R772[医药卫生—眼科]