多糖类药物治疗复发性口腔溃疡的疗效及影响因素  

Therapeutic effect and influencing factors of multi carbohydrate drugs in the treatment of recurrent oral ulcer

作　　者：李芳芳[1] 武云霞[2] LI Fang-fang WU Yun-xia(Department of oral medicine, Shanxi Medical University,Shanxi Taiyuan 030001,China Department of oral medicine, Shanxi Medical University,Shanxi Taiyuan 030001,China)

机构地区：[1]山西医科大学口腔医学系,山西太原030001 [2]山西医科大学第一医院口腔科,山西太原030001

出　　处：《全科口腔医学电子杂志》2016年第9期32-33,35,共3页Electronic Journal of General Stomatology

摘　　要：复发性口腔溃疡是一种临床多发的口腔粘膜性疾病,研究表明,免疫功能失调是其发病的重要机制,多糖类药物可通过调节细胞因子分泌,增加淋巴细胞数量及改善亚群的比例,促进淋巴细胞抗体分泌和表皮生长因子的表达等增强机体免疫功能,促进溃疡愈合。本文将对多糖类药物治疗复发性口腔溃疡的疗效及影响因素的研究进展予以综述。Recurrent oral ulcers is a clinical multiple oral mucosal disease, the study shows that immune dysfunction is an important mechanism of pathogenesis, polysaccharide drugs by regulating the secretion of cytokines, increase the number of lymphocytes and improve the proportion of subpopulations promoting lymphocyte antibody secretion and expression of epidermal growth factor to enhance immune function and promote the healing of ulcers. Progress efficacy and influencing factors of recurrent oral ulcers paper will polysaccharide drug treatment be reviewed.

关 键 词：复发性口腔溃疡 多糖类药物 细胞因子 淋巴细胞 

分 类 号：R781.5[医药卫生—口腔医学]