SOX化疗方案治疗对老年晚期胃癌患者免疫功能的影响  

Effects of SOX Chemotherapy on Immune Function in Elderly Patients with Advanced Gastric Cancer

作　　者：田彩[1] 杨继[1] 

机构地区：[1]河南宏力医院,河南新乡453400

出　　处：《医学新知》2017年第5期474-476,共3页New Medicine

摘　　要：目的 观察SOX化疗方案（奥沙利铂联合替吉奥）对老年晚期胃癌患者免疫功能的影响.方法选取2014年7月~2016年4月在我院接受化疗的老年晚期胃癌患者60例,根据随机数表法分为对照组及观察组（各30例）.对照组化疗采用替吉奥联合顺铂方案,观察组采用SOX方案.比较两组免疫功能改善情况及疗效.结果治疗后,观察组免疫功能相关指标水平高于对照组,观察组治疗总有效率高于对照组,差异均有统计学意义（P〈0.05）.结论SOX化疗方案治疗晚期胃癌老年患者临床疗效显著,患者免疫功能明显改善,预后好.Objective To observe effects of SOX chemotherapy（oxaliplatin ＋ s - 1 ） on immune functions in eld- erly patients with advanced gastric carcinoma. Methods 60 elderly patients with advanced gastric cancer who re- ceived chemotherapy in our hospital from Jul. 2014 to Apr. 2016 were randomly divided into control group and obser- vation group with 30 patients in each group. S - 1 combined with cisplatin were used in control group and SOX scheme was used in observation group. Improvement of immune function and curative effects were compared between the two groups. Results Immune function indexes were higher in observation group than those in control group after treatment （ P 〈 0.05 ）. The total efficiency was higher in observation group than that in control group（ P 〈 0.05 ）. Conclusion SOX chemotherapy regimen is effective in the treatment of elderly patients with advanced gastric cancer, which can improve immune function and have good prognosis.

关 键 词：SOX化疗方案 老年晚期胃癌 免疫功能 

分 类 号：R735.2[医药卫生—肿瘤]