颅骨骨巨细胞瘤影像表现：16例报告并文献分析  

Imaging of giant cell tumors of the skuli.a report of 16 cases and literature review

作　　者：金鹤[1] 李亚农[1] 武春雪[1] 王政[1] 马军[1] 

机构地区：[1]首都医科大学附属北京天坛医院神经影像中心,北京100050

出　　处：《实用放射学杂志》2017年第11期1657-1660,共4页Journal of Practical Radiology

摘　　要：目的分析颅骨骨巨细胞瘤（GCTs）的影像特点并文献分析。方法回顾性分析16例经病理证实的颅骨GCTs的CT及MR影像表现，并综述多篇文献报道的颅骨GCTs的影像特点。结果16例患者（男：女=9：7）病灶主要位于蝶骨、颢骨。于CT图像上，病灶多呈稍高密度，可见囊变；原发于鞍区蝶骨的GCTs邻近骨质多呈溶骨性破坏；原发于颞骨者多呈膨胀性骨质破坏，病灶内可见斑片状钙化密度影，周边可见不连续“骨包壳”。于MR图像上，病灶多呈T1WI等信号，T2WI等信号或低信号为主，可见囊变区；增强扫描病灶多呈不均匀明显强化，部分病灶邻近脑膜强化。结论颅骨GCTs主要发生于蝶骨、颞骨，原发部位不同者CT示骨质改变有所不同，MR图像上表现多样，T2WI多呈等信号或低信号为主。Objective To investigate the imaging features of giant cell tumors （GCTs） of the skull and review of the literatures. Methods CT and MR features of 16 histologically proven GCTs of the skull were analyzed retrospectively. The imaging features of GCTs of the skull were summarized based on literature.Results 16 patients （male= 9, female= 7）with GCTs of the skull were enrolled in the study.Most of the lesions were originated from sphenoid and temporal hone. On CT scan,the lesions showed slightly hyperdense with cystic formation. Those of the sphenoid bone in sellar region usually showed osteolytic bone destruction;those of the temporal bone usually showed expansive bone destruction,foei calcification in the lesion and discontinuous ~＇bony shell＂ sign could be seen at the edge.On MR images, the lesion showed isointense on T1 WI and iso-or hypointense on T2 WI with cystic formation.After contrast medium injection, the lesions demonstrated heterogeneous and apparent enhancement, and the enhancement of the adjacent meninges could be detected in some cases. Conclusion GCTs of the skull mainly originate from sphenoid and temporal bone, and the bone changes are different between the two sites on CT scan. The imaging features of GCTs are various on MR images and mainly show isointense or hypointense on T2 WI.

关 键 词：颅骨 骨巨细胞瘤 计算机体层成像 磁共振成像 

分 类 号：R738.1[医药卫生—肿瘤] R814.42[医药卫生—临床医学]