心叶青藤茎中酚类化学成分研究  

A study of phenolic compounds from the stems of Illigera cordata Dunn.

作　　者：代家猛 逯娅 黄相中[1] 钏永明[1] 普晓云 马司颖 阮榕生[1] 杨志 孙静贤[1] 

机构地区：[1]云南民族大学民族药资源化学国家民族事务委员会-教育部重点实验室,云南昆明650500 [2]云南白药集团创新中心,云南昆明650111

出　　处：《云南民族大学学报（自然科学版）》2017年第6期433-437,共5页Journal of Yunnan Minzu University:Natural Sciences Edition

基　　金：国家自然科学基金(81460535);云南省教育厅科学研究基金(2017YJS058);云南民族大学研究生创新基金(2016YJCXS16);云南民族大学大学生创业创新训练计划项目(16000416)

摘　　要：采用硅胶柱色谱、凝胶柱色谱及高效液相色谱等多种分离方法从药用植物莲叶桐科青藤属植物心叶青藤茎的体积分数95%乙醇提取物中分离得到11个酚类化合物.根据化合物的理化性质及波谱数据分析,将其分别鉴定为toddaculine(1),pentadienoic acid A(2),pentadienoic acid B(3),8-hydroxycarvacrol(4),8-ethoxythymol(5),(1S)-methoxy-1-(3,5-dimethoxy-4-hydroxyphenyl)ethane(6),4-ethyl-2,6-dimethoxyphenol(7),P-ethylguaiacol(8),4-methylresorcinol(9),2,6-dimethoxy-4-methylphenol(10),ethyl 4'-hydroxyphenylacetate(11).所有化合物均为首次从该种植物中分离得到.This phytochemical investigation on the chemical constituents of ethanol extracts from the stems of Illigera cordata Dunn has led to the isolation of eleven phenolic compounds by silica gel column chromatography,Sephadex LH-20,HPLC,et al. The structures of these compounds were elucidated on the basis of spectral data and compared with published data. The structures were identified as toddaculine(1),pentadienoic acid A(2),pentadienoic acid B(3),8-hydroxycarvacrol(4),8-ethoxythymol(5),(1 S)-methoxy-1-(3,5-dimethoxy-4-hydroxyphenyl) ethane(6),4-ethyl-2,6-dimethoxyphenol(7),P-ethylguaiacol(8),4-methylresorcinol(9),2,6-dimethoxy-4-methylphenol(10),ethyl 4'-hydroxyphenylacetate(11). All of the compounds were isolated from this plant for the first time.

关 键 词：心叶青藤 酚类化合物 化学成分 

分 类 号：R284.1[医药卫生—中药学]